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The deposition of circulating complement factor H-related (FHR) proteins in tissues around the body has been implicated in a series of complement-mediated diseases. However, the array of blood-borne binding partners with which they interact remains unclear. Here, we identify novel blood-borne bindin...
ORGANISM(S): Homo sapiens (Human) 
2026-03-30 | PXD072296 | Pride
Age-related macular degeneration (AMD) is a common form of adult blindness. Risk of developing AMD is strongly linked to genetics, in particular at the Regulators of Complement Activation (RCA) locus on Chr1, which contains 6 genes, Complement Factor H (CFH) and Complement Factor H-related 1-5 (CFHR...
ORGANISM(S): Homo Sapiens 
2022-01-18 | PXD023466 | panorama
Mapped data (bam files) for high-throughput whole genome sequence data for 83 modern Aboriginal Australians
Genotype calls for 83 Aboriginal Australian genomes split by chromosomes. In short, genotypes were called individually with samtools. They were subsequently filtered with thresholds related to sequencing depth, location of variants, sequencing error, and strand bias. Once combined, the genotypes wer...
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