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TranscriptomicsExpression profiling defines a recurrence signature in lung squamous cell carcinoma
Lung cancer remains the leading cause of cancer death worldwide. Overall 5-year survival is about 10-15% and despite curative intent surgery, treatment failure is primarily due to recurrent disease. Conventional prognostic markers are unable to determine which patients with completely resected disea...
ORGANISM(S): Homo sapiens 
2010-07-01 | E-GEOD-5123 | biostudies-arrayexpress
TranscriptomicsGene expression profiling classifies lung squamous cell carcinomas with N1 positive lymph nodes
Using gene expression microarrays, we tested whether lung SCCs that have metastasised to loco-regional lymph nodes (N1/2m) are different to those that directly invade and involve local nodes (N1d). Using 22,323 element microarrays, a non-parametric test identified 126 genes/transcripts that discrimi...
ORGANISM(S): Homo sapiens 
2007-05-01 | E-GEOD-5828 | biostudies-arrayexpress
TranscriptomicsADAM-28: A potential oncogene involved in asbestos-related lung adenocarcinomas
To identify gene expression biomarkers associated with asbestos-related lung adenocarcinoma, we analyzed primary tumour gene expression for a total of 36 primary lung adenocarcinomas on 22,323 element microarrays, comparing 12 patients with lung asbestos body counts above levels associated with urba...
ORGANISM(S): Homo sapiens 
2010-05-28 | E-GEOD-20875 | biostudies-arrayexpress
TranscriptomicsArray-Comparative Genomic Hybridization Reveals Loss of SOCS6 is Associated with Poor Prognosis in Primary Lung Squamous Cell Carcinoma
Primary tumor recurrence occurs commonly after surgical resection of lung squamous cell carcinoma (SCC). The aim of this study was to identify genes involved in recurrence in lung squamous cell carcinoma patients. Array comparative genomic hybridization (aCGH) was performed on DNA extracted from tum...
ORGANISM(S): Homo sapiens 
2011-12-25 | E-GEOD-32058 | biostudies-arrayexpress
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