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ProteomicsProteomic analysis of of the exoproteome of a clathrin mutant
Fungi are the most important plant pathogens on agricultural and horticultural crops. Study of these pathogens remains essential to understand pathogenic process and control plant diseases. In this context, a random insertional mutagenesis strategy, based on the Agrobacterium tumefaciens-mediated tr...
ORGANISM(S): Botryotinia fuckeliana (strain B05.10) (Noble rot fungus) (Botrytis cinerea) 
2021-06-11 | PXD023460 | Pride
Phytopathogneic fungus Virulence Quantitative proteome Clathrin mutant 
TranscriptomicsIdentification of a Potently Oncogenic CALM-AF10 Minimal-Fusion Mutant
This SuperSeries is composed of the following subset Series: GSE27512: Identification of a Potently Oncogenic CALM-AF10 Minimal-Fusion Mutant (miRNA) GSE27513: Identification of a Potently Oncogenic CALM-AF10 Minimal-Fusion Mutant (mRNA) Refer to individual Series
ORGANISM(S): Mus musculus 
2011-10-04 | E-GEOD-27514 | biostudies-arrayexpress
TranscriptomicsIdentification of a Potently Oncogenic CALM-AF10 Minimal-Fusion Mutant (miRNA)
The t(10;11) p (13;q14) translocation, giving rise to CALM-AF10, is a recurring chromosomal translocation observed in several types of acute leukemias as well as in lymphoma. We have previously demonstrated that the expression of the human CALM/AF10 fusion gene in murine bone marrow stem and progeni...
ORGANISM(S): Mus musculus 
2011-10-04 | E-GEOD-27512 | biostudies-arrayexpress
TranscriptomicsIdentification of a Potently Oncogenic CALM-AF10 Minimal-Fusion Mutant (mRNA)
The t(10;11) p (13;q14) translocation, giving rise to CALM-AF10, is a recurring chromosomal translocation observed in several types of acute leukemias as well as in lymphoma. We have previously demonstrated that the expression of the human CALM/AF10 fusion gene in murine bone marrow stem and progeni...
ORGANISM(S): Mus musculus 
2011-10-04 | E-GEOD-27513 | biostudies-arrayexpress
UnknownCharacterization of a temperature-sensitive vertebrate clathrin heavy chain mutant as a tool to study clathrin-dependent events in vivo.
Not available
S-EPMC2917355 | biostudies-literature
ProteomicsCalcium-triggered (de)ubiquitination events in synapses
Neuronal communication relies on neurotransmitter release from synaptic vesicles (SVs), whose dynamics are controlled by Ca2+-dependent pathways, as many thoroughly studied phosphorylation cascades. However, little is known about other post-translational modifications, as ubiquitination. To address ...
ORGANISM(S): Homo Sapiens Rattus Norvegicus 
2025-04-19 | PXD053470 | panorama
ProteomicsWnt signalosome assembly is governed by conformational flexibility of Axin and AP2 clathrin adaptor
Wnt signal transduction relies on the direct inhibition of GSK3 by phosphorylated PPPSPxS motifs within the cytoplasmic tail of the LRP6 co-receptor. How GSK3 is recruited to LRP6 remains unclear. Here, we use nuclear magnetic resonance spectroscopy to identify the membrane-proximal PPPSPxS motif an...
ORGANISM(S): Xenopus laevis (African clawed frog) 
2025-04-30 | PXD061649 | Pride
Gsk3 inhibition  lrp6 co-receptor  axin scaffold protein  ap2 cargo adaptor  clathrin-coated structures  wnt signalosome 
UnknownAn assembly-incompetent mutant establishes a requirement for dynamin self-assembly in clathrin-mediated endocytosis in vivo.
Not available
S-EPMC404019 | biostudies-literature
UnknownClathrin-independent endocytosis of ubiquitinated cargos.
Not available
S-EPMC549482 | biostudies-literature
ProteomicsSwiprosin1 controls cargo-specific entry to clathrin and dynamin-independent endocytic pathway
The clathrin and dynamin-independent endocytic pathway (CLIC-GEEC) is the major route of internalization of a large fraction of glycosylphosphatidylinositol-anchored proteins (GPI-APs) and other cell surface receptors. Unlike the clathrin-dependent endocytic pathway, where adaptors recruited to the ...
ORGANISM(S): Homo sapiens (Human) 
2021-08-18 | PXD016478 | Pride
Human Endocytosis Rab21 Swiprosin Clathrin-independent Silac Co-ip 
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