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ProteomicsLC-MS/MS of Rab21 pull-down or control sample
LC-MS/MS of Rab21 pull-down or control sample from 786-O cells
ORGANISM(S): Homo sapiens (Human) 
2023-10-24 | PXD033104 | Pride
Human Rab21 Lc-ms/ms 
GenomicsPhenotypic screens for SIRPA expression reveal RAB21 as a general regulator of macrophage surface identity
Phenotypic screens for SIRPA expression reveal RAB21 as a general regulator of macrophage surface identity
PRJNA1262991 | ENA
ProteomicsSwiprosin1 controls cargo-specific entry to clathrin and dynamin-independent endocytic pathway
The clathrin and dynamin-independent endocytic pathway (CLIC-GEEC) is the major route of internalization of a large fraction of glycosylphosphatidylinositol-anchored proteins (GPI-APs) and other cell surface receptors. Unlike the clathrin-dependent endocytic pathway, where adaptors recruited to the ...
ORGANISM(S): Homo sapiens (Human) 
2021-08-18 | PXD016478 | Pride
Human Endocytosis Rab21 Swiprosin Clathrin-independent Silac Co-ip 
OtherPhenotypic screens for SIRPA expression reveal RAB21 as a general regulator of macrophage surface identity
Factors influencing the macrophage surfaceome define macrophage identity and behaviour. Here, we use genome-wide phenotypic screens to identify genes affecting the accessibility and surface expression of macrophage SIRPA. Our data are consistent with previous evidence but also implicate QPCTL in cis...
ORGANISM(S): Homo sapiens Mus musculus 
2025-06-03 | GSE297202 | GEO
ProteomicsAn early endosomal network participates to enterocyte functions and intestinal homeostasis
Membrane trafficking is defined as the vesicular transport of molecules throughout the cell. In intestinal enterocytes, defects in endocytic/recycling pathways impair their function and are linked to genetic diseases. How does trafficking regulate intestinal tissue homeostasis is poorly understood. ...
ORGANISM(S): Drosophila melanogaster (Fruit fly) 
2022-08-12 | PXD022413 | Pride
Intestine Tmt Drosophila Rab21 
UnknownRab21 in enterocytes participates in intestinal epithelium maintenance.
Not available
S-EPMC9250356 | biostudies-literature
UnknownRAB21 interacts with TMED10 and modulates its localization and abundance.
Not available
S-EPMC6777364 | biostudies-literature
UnknownDynamic changes in the spatiotemporal localization of Rab21 in live RAW264 cells during macropinocytosis.
Not available
S-EPMC2726762 | biostudies-literature
ProteomicsEPLINα controls integrin recycling from Rab21 endosomes to drive breast cancer cell migration
EPLIN, an actin-binding protein, has been described as both a tumor promoter and tumor suppressor in different cancers. The roles of EPLIN isoforms (α/β) remain largely unknown and could explain these opposing views. We observed distinct EPLIN isoform localization in breast cancer cells; EPLINα is r...
ORGANISM(S): Homo sapiens (Human) 
2025-08-26 | PXD052819 | Pride
Bioid Breast cancer Lc-msms Human 
UnknownProteomics analysis reveals elevated RAB21 in serum-derived extracellular vesicles from patients with follicular thyroid carcinoma.
Not available
S-EPMC12308455 | biostudies-literature
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