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TranscriptomicsTranscriptional profiling by array to study the effect of adenoviruses encoding the FLAG epitope or full-length antisense sequence to Atf3 on transcriptional regulation in rat cardiac myocytes
Cardiomyocytes, the terminally-differentiated contractile cells of the heart, undergo hypertrophic growth in response to endothelin-1. This is associated with changes in mRNA expression of immediate early genes (IEGs). Atf3 is a member of the ATF/CREB family transcription factors which bind as dim...
ORGANISM(S): Rattus norvegicus 
2012-10-01 | E-MEXP-3392 | biostudies-arrayexpress
TranscriptomicsEffect of 30 or 90 min exposure to endothelin-1 on the cardiac myocyte transcriptome
Cardiac myocytes were exposed to 100 nM endothelin-1 for 30 or 90 min to determine effects on mRNA expression using Exon arrays
ORGANISM(S): Rattus norvegicus 
2012-10-01 | E-MEXP-3393 | biostudies-arrayexpress
TranscriptomicsEffect of 60 min exposure to endothelin-1 on the cardiac myocyte transcriptome
Cardiac myocytes were unstimulated or exposed to 100 nM endothelin-1 for 60 min
ORGANISM(S): Rattus norvegicus 
2012-10-01 | E-MEXP-3394 | biostudies-arrayexpress
TranscriptomicsTranscription and translation profiling of rat cardiomyocytes treated with insulin
Effect of insulin on the cardiomyocyte global transcriptome and RNAs recruited to polysomes.
For comparison with endothelin-1
ORGANISM(S): Rattus norvegicus 
2010-07-04 | E-MEXP-2527 | biostudies-arrayexpress
TranscriptomicsTranscription profiling by array of Rattus norvegicus cardiomyocytes to investigate the effects of 30 or 60 min phenylephrine exposure on gene expression
Rat neonatal cardiomyocytes were exposed to 100 uM phenylephrine for 0, 30 or 60 mins
ORGANISM(S): Rattus norvegicus 
2013-01-16 | E-MEXP-3678 | biostudies-arrayexpress
TranscriptomicsTranscription profiling by array of Rattus norvegicus cardiomyocytes to investigate the effects of PD184352 and BI-D1870 on changes in expression induced by endothelin-1
Cardiomyocytes were exposed to PD184352, BI-D1870 or endothelin-1 alone, or to endothelin-1 in the presence of each inhibitor
ORGANISM(S): Rattus norvegicus 
2013-01-16 | E-MEXP-3679 | biostudies-arrayexpress
TranscriptomicsTranscriptional profiling of rat heart ventricular myocytes treated either with PD184352 alone or PD184352 and endothelin-1.
Effects of PD184352 on RNA profiles in neonatal rat cardiomyocytes exposed to endothelin-1
ORGANISM(S): Rattus norvegicus 
2010-05-26 | E-MEXP-2516 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of rat neonatal ventricular cardiac mycocytes exposed to endothelin-1 and C3 toxin
Effects of C3 toxin on RNA profiles in neonatal rat ventricular cardiac myocytes exposed to endothelin-1 (1 h)
ORGANISM(S): Rattus norvegicus 
2010-05-25 | E-MEXP-1977 | biostudies-arrayexpress
TranscriptomicsTranscription profiling by array of rat ventricular cardiac myocytes treated with interleukin 1 beta
Study of the effects of interleukin 1 beta on transcript expression in ventricular cardiac myocytes
ORGANISM(S): Rattus norvegicus 
2010-04-01 | E-MEXP-1960 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of neonatal rat ventricular cardiac myocytes treated with interleukin 33 for 0.5, 1 or 2 hours
Study of the effect of interleukin 33 (IL33) on transcript expression in neonatal rat ventricular cardiac myocytes at 0.5, 1 or 2 h
ORGANISM(S): Rattus norvegicus 
2010-04-01 | E-MEXP-1912 | biostudies-arrayexpress
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