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ProteomicsCLIC4 interacting proteins - To identify proteins in human pulmonary artery endothelial cells that interact with CLIC4
To identify proteins in human pulmonary artery endothelial cells that interact with CLIC4
ORGANISM(S): Homo sapiens (Human) 
2018-10-16 | PXD008709 | Pride
Clic4 Human Endothelial cells Interacting proteins 
ProteomicsProteomics of CLIC4 overexpressing human pulmonary artery endothelial cells
To identify CLIC4 effectors by studying proteins expressiosn altered by CLIC4 overexpression in human pulmonary artery endothelial cells.
ORGANISM(S): Homo sapiens (Human) 
2018-10-16 | PXD008714 | Pride
Proteomics Endothelial cells Human Clic4 
GenomicsHost CLIC4 is essential for breast cancer metastatic competence
Host CLIC4 is essential for breast cancer metastatic competence
PRJNA767846 | ENA
TranscriptomicsHost CLIC4 is essential for breast cancer metastatic competence
Chloride Intracellular Channel 4 (CLIC4) expression is elevated in the stroma of many cancers. We show that CLIC4 expression is higher in breast cancers from younger women and early stage metastatic disease, portends poor prognosis, and is linked to TGF-β expression. Two murine breast cancer models ...
ORGANISM(S): Mus musculus 
2022-05-25 | GSE185163 | GEO
UnknownCLIC4/Arf6 Pathway.
Not available
S-EPMC6325770 | biostudies-literature
GenomicsCLIC4 deficiency alters mitochondrial function and transcriptional profiles in murine breast cancer cells.
CLIC4 deficiency alters mitochondrial function and transcriptional profiles in murine breast cancer cells.
PRJNA727829 | ENA
TranscriptomicsCLIC4 is essential for host competence for metastasis in murine models of breast cancer and a prognostic indicator for human breast cancer
CLIC4 belongs to a family of highly conserved metamorphic proteins of the glutathione‐S‐transferase superfamily and dysregulation is implicated in pulmonary arterial hypertension, asthma, and ovarian cancer. We show that genetic ablation of host Clic4 eliminated the establishment of breast cancer lu...
ORGANISM(S): Mus musculus 
2020-11-26 | GSE141057 | GEO
UnknownCLIC4 is a tumor suppressor for cutaneous squamous cell cancer.
Not available
S-EPMC3334517 | biostudies-literature
UnknownCrosstalk between tumor and stroma modifies CLIC4 cargo in extracellular vesicles.
Not available
S-EPMC10803055 | biostudies-literature
GenomicsCLIC4 is essential for host competence for metastasis in murine models of breast cancer and a prognostic indicator for human breast cancer
CLIC4 is essential for host competence for metastasis in murine models of breast cancer and a prognostic indicator for human breast cancer
PRJNA591906 | ENA
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