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TranscriptomicsThe alternative complement pathway appears to be a UVA sensor that leads to systemic immunosuppression
Ultraviolet (UV) wavebands in sunlight are immunomodulatory. About half the amount of UVA within a minimum erythemal dose of sunlight is systemically immunosuppressive, while higher doses protect from UVB immunosuppression in mice. We have previously shown that these responses to UVA are genetically...
ORGANISM(S): Mus musculus 
2010-05-16 | E-GEOD-15618 | biostudies-arrayexpress
UnknownA method for increasing electroporation competence of Gram-negative clinical isolates by polymyxin B nonapeptide.
Not available
S-EPMC9270391 | biostudies-literature
ProteomicsRetroviral transduction of NOTCH1 into primary human Chronic Lymphocytic Leukemia cells unravels immune escape-mechanisms
Functional studies to investigate gene mutations recurrent in B cell lymphoma have been hampered by the inability to genetically manipulate primary cells, attributed to low transduction efficacy and procedure-associated toxicity. Alternative approaches utilize cell lines and mouse models, which ofte...
ORGANISM(S): Homo sapiens (Human) 
2022-08-26 | PXD024112 | Pride
Notch1 Mutated gene Chronic lymphocytic leukemia (cll) Co-activator ciita Mantle cell lymphoma (mcl) Hla-class ii locus 
MetabolomicsComparative characterization of the infant gut microbiome and their maternal lineage by a multi-omics approach

The human gut microbiome establishes and matures during infancy, and dysregulation at this stage may lead to pathologies later in life. We conducted a multi-omics study comprising three generations of family members to investigate the early development of the gut microbiota. Fecal samples from 20...

2024-03-07 | MTBLS7670 | MetaboLights
UnknownReciprocity, culture and human cooperation: previous insights and a new cross-cultural experiment.
Not available
S-EPMC2689715 | biostudies-literature
ProteomicsZAP-70 promotes microenvironment interactions and increases protein-translation in chronic lymphocytic leukemia
The expression of ZAP-70 in a subset of CLL patients strongly correlates with a more aggressive clinical course, though the exact underlying mechanisms remain elusive. The ability of ZAP-70 to enhance B cell receptor (BCR) signaling, independently of its kinase function, likely contributes. Here we ...
ORGANISM(S): Homo sapiens (Human) 
2022-08-26 | PXD019465 | Pride
Zap70 Q-plex_rime Leukemia 
UnknownStated and revealed inequality aversion in three subject pools.
Not available
S-EPMC4826595 | biostudies-literature
UnknownACE2-lentiviral transduction enables mouse SARS-CoV-2 infection and mapping of receptor interactions.
Not available
S-EPMC8282004 | biostudies-literature
UnknownConditioning on What? Heterogeneous Contributions and Conditional Cooperation.
Not available
S-EPMC5788275 | biostudies-literature
TranscriptomicsTranscription profiling of hippocampus of CV mice (C57Bl x VM/Dk) inoculated with ME7 scrapie to determine the molecular events that accompany the scrapie-associated hippocampal neuropathology
A study of differential gene expression in the hippocampus of CV mice (C57Bl x VM/Dk) inoculated with ME7 scrapie to determine the molecular events that accompany the scrapie-associated hippocampal neuropathology. Analysis was performed at 170 days post infection, a timepoint that coincides with se...
ORGANISM(S): Mus musculus 
2005-05-01 | E-MEXP-284 | biostudies-arrayexpress
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