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GenomicsThe Dutch retinoblastoma research team from the VU University medical center
Data Access Committee EGAC00001000431
EGAC00001000431 | EGA
GenomicsCopy number profiling of primary samples and cell lines of retinoblastoma
Illumina SNP-arrays for matching retinoblastoma-blood pairs and retinoblastoma cell lines.
EGAD00010000908 | EGA
GenomicsCopy number profiling of primary samples and cell lines of retinoblastoma
While RB1 loss initiates retinoblastoma development, additional somatic copy number alterations (SCNAs) can drive tumor progression. Although SCNAs have been identified with good concordance between studies at a cytoband resolution, accurate identification of single genes for all recurrent SCNAs is ...
EGAS00001001715 | EGA
Genomicsena-DATASET-VIB-CME-16-05-2014-16:10:17:695-121 - samples
Description not provided
EGAD00001000849 | EGA
GenomicsIdentification of point mutations, expression perturbations, and gene fusions in T-cell acute lymphoblastic leukemia by RNA-seq
RNA-seq is a promising technology to re-sequence protein-coding genes for the identification of single nucleotide variants, while simultaneously obtaining information on structural variations and gene expression perturbations. T-cell acute lymphoblastic leukemia (T-ALL) is caused by a combination of...
EGAS00001000536 | EGA
GenomicsVIB Institutional DAC
Data Access Committee EGAC00001002939
EGAC00001002939 | EGA
Genomicsena-DATASET-VUMC-CCA-03-02-2016-12:25:24:488-68 - samples
Paired-end whole exome sequenncing (Illumina) of primary enucleated retinoblastoma and matching lymphocyte DNA was performed to find somatic alterations that are related to oncogenesis.
EGAD00001001909 | EGA
GenomicsWhole exome sequencing on primary retinoblastoma tissues and matching lymphocyte DNA.
Retinoblastoma is a rare childhood cancer initiated by RB1 mutation or MYCN amplification, while additional alterations may be required for tumor development. However, the view on single nucleotide variants is very limited. To better understand oncogenesis, we determined the genomic landscape of ret...
EGAS00001001690 | EGA
ProteomicsHuman AML secretome and exosomes and correlation with Anti-Apoptotic Index, part 3
Expression of proteins regulating apoptosis (BCL-2, MCL-1, BCL-X and BAX) in acute myeloid leukemia (AML) blasts at diagnosis have been shown to be associated with disease-free survival. We previously found that the initially high apoptosis-resistance of AML cells decreased after therapy, while rega...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2016-10-21 | MSV000080268 | MassIVE
ProteomicsHuman AML secretome and exosomes and correlation with Anti-Apoptotic Index, part 4
Expression of proteins regulating apoptosis (BCL-2, MCL-1, BCL-X and BAX) in acute myeloid leukemia (AML) blasts at diagnosis have been shown to be associated with disease-free survival. The concentrations of these proteins are combined in the Anti Apoptotic index (AAI). We previously found that th...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2016-10-21 | MSV000080266 | MassIVE
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