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ProteomicsMapping the GW182 CIM1 binding site on CNOT1(800-999) by HDX-MS
HDX-MS experiments were performed as described in detail in Białobrzewski M.K., Cieplak-Rotowska M.K., et al (https://www.biorxiv.org/content/10.64898/2026.07.16.738963v1) on human CNOT1 (residues 800-999) in the presence of peptides corresponding to GW182 CIM1 (QSRLPQWTHP), N-CIM1 (DPSQSQSRLPQWTHPN...
ORGANISM(S): Homo sapiens (Human) 
2026-08-20 | PXD082855 | Pride
Cnot1 Hdx-ms 
GenomicsRibosome Profiling with CNOT1 depletion
Ribosome Profiling with CNOT1 depletion
PRJNA664116 | ENA
TranscriptomicsRNA-seq of livers in control and Cnot1 tamoxifen-inducible liver-specific knockout mice
Gene expression is balanced by transcription and mRNA degradation. Shortening of polyadenosine (poly(A)) tails (deadenylation) is the initial step in the decay of most mRNAs. However, the mechanism by which deadenylation controls mRNA expression is not fully understood. This experiment aimed to dete...
ORGANISM(S): Mus musculus 
2020-03-30 | E-MTAB-5901 | biostudies-arrayexpress
GenomicsChIP-seq of livers in control and Cnot1 tamoxifen-inducible liver-specific knockout mice
Gene expression is balanced by transcription and mRNA degradation. Shortening of polyadenosine (poly(A)) tails (deadenylation) is the initial step in the decay of most mRNAs. However, the mechanism by which deadenylation controls mRNA expression is not fully understood. This experiment aimed to dete...
ORGANISM(S): Mus musculus 
2020-03-30 | E-MTAB-5887 | biostudies-arrayexpress
GenomicsCNOT1 and Transcriptomic Landscape of a HeLa Cell Line
CNOT1 and Transcriptomic Landscape of a HeLa Cell Line
PRJNA593610 | ENA
UnknownCNOT1 cooperates with LMNA to aggravate osteosarcoma tumorigenesis through the Hedgehog signaling pathway.
Not available
S-EPMC5527480 | biostudies-literature
TranscriptomicsRibosome Profiling with CNOT1 depletion
Ribosome profiling in HEK293 cells with and without the depletion of CNOT1. This allows the determination of translational efficiency and nucleotide resolution of ribosome occupancy.
ORGANISM(S): Homo sapiens 
2021-08-23 | GSE158141 | GEO
UnknownA CCR4-NOT Transcription Complex, Subunit 1, CNOT1, Variant Associated with Holoprosencephaly.
Not available
S-EPMC6506867 | biostudies-literature
GenomicsmRNA stability experiments with control or CNOT1-targeting siRNA treatment in HEK293 cells
mRNA stability experiments with control or CNOT1-targeting siRNA treatment in HEK293 cells
PRJNA665988 | ENA
UnknownHuman DDX6 effects miRNA-mediated gene silencing via direct binding to CNOT1.
Not available
S-EPMC4138323 | biostudies-literature
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