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Autism Spectrum disorder (ASD) is a heterogeneous neurodevelopmental disorder where patients have impaired social behavior and communication, and restricted interests. Although various studies have been carried out to unveil the mechanisms associated with ASD, its pathophysiology is still poorly und...
ORGANISM(S): Mus musculus (Mouse) 
2023-03-11 | PXD031656 | Pride
This study identifies conserved protein biomarkers for Autism Spectrum Disorder (ASD) using a cross-species proteomic approach. Proteomic analyses were conducted on serum and brain samples from CNTNAP2 knockout (KO) mice and human ASD patient serum. A total of 132 conserved proteins were identified,...
ORGANISM(S): Homo sapiens (Human) 
2026-02-23 | PXD060810 | Pride
Developmental Deficits of MGE-derived Interneurons in the Cntnap2 Knockout Mouse Model of Autism Spectrum Disorder
Interneurons are fundamental cells for maintaining the excitation-inhibition balance in the brain in health and disease. While interneurons have been shown to play a key role in the pathophysiology of autism spectrum disorder (ASD) in adult mice, little is known about how their maturation is altered...
ORGANISM(S): Mus musculus 
2023-01-12 | GSE222383 | GEO
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