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Unknown'Know thyself' - host factors influencing cancer response to immune checkpoint inhibitors.
Not available
S-EPMC9320825 | biostudies-literature
UnknownCD137L and CD4 T cells limit BCL6-expressing pre-germinal center B cell expansion and BCL6-driven B cell malignancy.
Not available
S-EPMC9805071 | biostudies-literature
MetabolomicsA combined direct infusion/reversed phase chromatography – high resolution mass spectrometry workflow for accurate absolute lipid quantification with 13C- internal standards
We propose a fully automated novel workflow for lipidomics based on flow injection, followed by liquid chromatography-high-resolution mass spectrometry (FI/LC-HRMS). The workflow combined in-depth characterization of the lipidome achieved via reversed-phase LC-HRMS with absolute quantification by us...
2021-07-01 | MTBLS1876 | MetaboLights
TranscriptomicsTranscription profiling by array of Bacillus thuringiensis Bt407 overexpressing transcriptional regulator MogR versus an empty vector (pHT304-Pxyl) control strain during late exponential growth
Comparison in late exponential phase (culture OD600 = 3) of global expression profiles from a Bacillus thuringiensis 407 strain overexpressing transcriptional regulator MogR from xylose inducible vector pHT304-Pxyl, versus an isogenic empty vector control strain, to analyze global expression changes...
ORGANISM(S): Bacillus thuringiensis 
2020-09-28 | E-MTAB-7633 | biostudies-arrayexpress
TranscriptomicsTemporal pattern of skeletal muscle gene expression following endurance exercise in Alaskan sled dogs
Background: Muscle responses to exercise are complex, and potentially include acute responses to exercise-induced injury as well as longer-term adaptive training responses. Using Alaskan sled dogs as an experimental model, changes in muscle gene expression were analyzed to better understand the tem...
ORGANISM(S): Canis lupus familiaris 
2010-05-16 | E-GEOD-15117 | biostudies-arrayexpress
TranscriptomicsTranscription profiling by array of Bacillus thuringiensis Bt407 overexpressing the diguanylate cyclase CdgF (BTB_c06420) versus an empty vector (pHT304-Pxyl) control strain 2 hours into post-exponential growth
Comparison of global expression profiles from a Bacillus thuringiensis 407 strain overexpressing the diguanylate cyclase CdgF (BTB_c06420) from the xylose inducible vector pHT304-Pxyl, versus an isogenic empty vector control strain, to analyze global expression changes resulting from CdgF overexpres...
ORGANISM(S): Bacillus thuringiensis Bt407 
2020-09-28 | E-MTAB-8898 | biostudies-arrayexpress
Transcriptomicswild-type and gaf1 mutant cells treated with Torin1 or with a combination of caffeine/rapamycin
Target of Rapamycin Complex 1 (TORC1) signaling promotes growth and ageing. Inhibition of TORC1 leads to a down-regulation of factors that stimulate protein translation, which in turn contributes to longevity. TORC1-dependent post-transcriptional regulation of protein translation has been well studi...
ORGANISM(S): Schizosaccharomyces pombe 
2020-03-02 | E-MTAB-8569 | biostudies-arrayexpress
TranscriptomicsExpression profile of Ewing sarcoma and osteosarcoma
The expression profile of primary pediatric Ewing sarcoma (ES) and osteosarcoma (OS) were analyzed. 8 Ewing sarcoma patient samples (TUM-ES0XXX) and 10 osteosarcoma patient samples (TUM-OS0XXX) were analyzed.
ORGANISM(S): Homo sapiens 
2016-07-05 | E-GEOD-73166 | biostudies-arrayexpress
UnknownOncolytic Virotherapy Promotes Intratumoral T Cell Infiltration and Improves Anti-PD-1 Immunotherapy.
Not available
S-EPMC8034392 | biostudies-literature
TranscriptomicsTargeting IRAK1 as a therapeutic approach for Myelodysplastic Syndrome
Myelodysplastic Syndromes (MDS) result from expansion of defective hematopoietic stem/progenitor clones. There is an urgent need to develop targeted therapies capable of eliminating the defective MDS clones. We identified that IRAK1, an immune modulating kinase, is overexpressed and hyperactivated i...
ORGANISM(S): Homo sapiens 
2013-04-25 | E-GEOD-46346 | biostudies-arrayexpress
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