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TranscriptomicsDetermining the M. smegmatis DosR regulon
DosR is the regulator of a two-component system in mycobacteria that senses oxygen concentration and the redox state of the cells. To determine the DosR regulon, the transcriptomes of M. smegmatis mc2155 and the M-NM-^TdosR cells were compared by microarray at 10 hours following induction of oxygen-...
ORGANISM(S): Mycobacterium smegmatis 
2014-07-10 | E-GEOD-56083 | biostudies-arrayexpress
TranscriptomicsTransciptional profile of a M. smegmatis mc2155 ΔsigF strain under standard growth conditions
Comparing transciptional profile of a M. smegmatis mc2155 ΔsigF strain and wild type (control) in in vitro culture at two time points (exponential phase and stationary phase) for identification of SigF-dependent genes. Analysis of 2 time points: exponential and stationary phase. 4 biological replic...
ORGANISM(S): Mycobacterium smegmatis 
2010-06-05 | E-GEOD-19145 | biostudies-arrayexpress
TranscriptomicsH4K16ac(M).14-16 hr OR embryo
modENCODE_submission_3698 This submission comes from a modENCODE project of Gary Karpen. For full list of modENCODE projects, see http://www.genome.gov/26524648 Project Goal: We aim to determine the locations of the major histone modifications across the Drosophila melanogaster genome. The modificat...
ORGANISM(S): Drosophila melanogaster 
2013-02-22 | E-GEOD-44474 | biostudies-arrayexpress
TranscriptomicsMeiotic DNA double strand breaks in the yeast Saccaromyces cerevisiae
DNA double-strand breaks (DSBs) initiate meiotic recombination. Past DSB-mapping studies have used rad50S or sae2? mutants, which are defective in break processing, to accumulate DSBs, and report large (= 50 kb) “DSB-hot” regions that are separated by “DSB-cold” domains of similar size. Substantial ...
ORGANISM(S): Saccharomyces cerevisiae 
2007-12-30 | E-GEOD-8981 | biostudies-arrayexpress
GenomicsH4K16ac(M).14-16 hr OR embryo.Solexa
modENCODE_submission_4938 This submission comes from a modENCODE project of Gary Karpen. For full list of modENCODE projects, see http://www.genome.gov/26524648 Project Goal: We aim to determine the locations of the major histone modifications across the Drosophila melanogaster genome. The modificat...
ORGANISM(S): Drosophila melanogaster 
2013-05-28 | E-GEOD-47245 | biostudies-arrayexpress
TranscriptomicsTranscriptomes profile of Solanum tuberosum (St) and Solanum commersonii (Sc) under cold stress and AtCBF3 overexpression.
St (common potato) is a freezing sensitive species unable to cold acclimate. The close wild relative Sc is freezing tolerant and able to cold acclimate. Here we compare the cold transcriptome of these two species with different levels of freezing tolerance. We also identify the putative CBF regulons...
ORGANISM(S): Solanum tuberosum 
2011-04-30 | E-GEOD-22449 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of the Arctic springtail Megaphorura arctica after cold or salt dehydration to study insect cyroprotective dehydration
The 13,824 cDNA microarray was constructed by printing 6912 PCR-amplified cDNA clones in duplicate. These were derived from a previous EST study (Clark et al, 2007) and comprised 3840 clones from the Library D2 (fully dehydrated animals, cooled to -14°C) and 3072 clones from the Library D1 (dehydrat...
ORGANISM(S): Megaphorura arctica 
2009-07-21 | E-MEXP-2105 | biostudies-arrayexpress
TranscriptomicsArray-Based Genomic Comparative Hybridization Analysis of Field Strains of Mycoplasma hyopneumoniae
Mycoplasma hyopneumoniae is the causative agent of porcine enzootic pneumonia and a major factor in the porcine respiratory disease complex. A clear understanding of the mechanisms of pathogenesis does not exist although it is clear that M. hyopneumoniae adheres to porcine ciliated epithelium by act...
ORGANISM(S): Mycoplasma hyopneumoniae 
2010-05-27 | E-GEOD-8306 | biostudies-arrayexpress
ProteomicsAlterations in the sputum proteome and transcriptome in smokers and early-stage COPD patients
Chronic obstructive pulmonary disease (COPD) is one of the most prevalent lung diseases, and involves persistent airflow limitation and incorporates both emphysema and chronic bronchitis. Cigarette smoking has been identified as the main risk factor for disease development and progression. In a basi...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2016-10-21 | MSV000080275 | MassIVE
TranscriptomicsTranscription profiling of the Antarctic springtail Cryptopygus antarcticus kept at -15 to 2 degrees C to investigate cold tolerance
The ability of the Antarctic microarthropod, Cryptopygus antarcticus (Collembola, Isotomidae), to survive low temperatures has been well studied at the physiological level. These investigations have indicated the importance of the moulting process in conferring this ability. This study investigated ...
ORGANISM(S): Cryptopygus antarcticus 
2009-12-01 | E-MEXP-2262 | biostudies-arrayexpress
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