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TranscriptomicsHigh-resolution, genome-wide analysis of human medulloblastoma samples by array-Comparative Genomic Hybridization (aCGH)
Medulloblastoma (MB) is the most common pediatric brain tumor and is an aggressive neoplasia arising in the cerebellum. MB includes four major histological subsets commonly subdivided in: classic, desmoplastic, anaplastic or large-cell, and nodular. The current patients risk stratification is based ...
ORGANISM(S): Homo sapiens 
2011-01-01 | E-GEOD-23005 | biostudies-arrayexpress
TranscriptomicsmiRNA expression profiling in high-risk neuroblastoma
In the present study we evaluated the miRNA expression profile of 31 high risk, stage 4 neuroblastoma patients. We compared miRNA expression profiles of 14 long-survivors (alive with an overall survival time > 36 months) and 17 short-survivors (dead of disease within 36 months from diagnosis. Deaths...
ORGANISM(S): Homo sapiens 
2010-05-16 | E-GEOD-16444 | biostudies-arrayexpress
TranscriptomicsHigh-resolution, genome-wide analysis of human metastatic neuroblastoma samples by array-Comparative Genomic Hybridization (aCGH)
Neuroblastoma (NB) is an aggressive tumor that affects both infants and children. The disease outcome is greatly influenced by age of patient, stage, chromosome copy number aberrations (CNAs) and gene expression abnormalities. We analyzed, by microarray technology, genome and transcriptome of 3 grou...
ORGANISM(S): Homo sapiens 
2012-01-01 | E-GEOD-25771 | biostudies-arrayexpress
TranscriptomicsHigh-resolution, genome-wide analysis of human metastatic neuroblastoma samples by array-Comparative Genomic Hybridization (aCGH)
Less than 30% of children with high-risk (HR) metastatic neuroblastoma (NB) show a long survival (Pearson 2000). In order to identify novel molecular prognostic markers useful to better predict patientsM-bM-^@M-^Y relapse risk estimation, we performed genome- and/or transcriptome-wide analyses of 12...
ORGANISM(S): Homo sapiens 
2012-10-05 | E-GEOD-35953 | biostudies-arrayexpress
TranscriptomicsGenomic aberrations in distant fields from oral potentially malignant lesions by high resolution DNA flow cytometry and array-CGH
The aim of the study was to address the concept of field cancerization in oral cancer. The presence of genomic aberrations, indicative of chromosomal instability (CIN), in oral distant fields (ODFs) of visually normal and non-dysplastic mucosa at the mirror image from concomitant oral potentially ma...
ORGANISM(S): Homo sapiens 
2011-12-21 | E-GEOD-28906 | biostudies-arrayexpress
TranscriptomicsChromosomal aberrations and aneuploidy in oral potentially malignant lesions: distinctive features for tongue.
The mucosae of the oral cavity are different at the histological level but are all exposed to common genotoxic agents. As a result of this exposure, changes in the mucosal epithelia develop giving rise to Oral Potentially Malignant Lesions (OPMLs), which with time may in turn progress to Oral Squamo...
ORGANISM(S): Homo sapiens 
2011-10-19 | E-GEOD-28868 | biostudies-arrayexpress
TranscriptomicsGene Expression profiles of human pediatric medulloblastoma
Medulloblastoma (MB) is one of the most common malignant pediatric brain tumor. The aim of our study was to understand which mechanisms are involved in aberrant activation of Wnt pathway and its association with MB tumor development. We studied the expression profiles of 19 MBs tumors using a genome...
ORGANISM(S): Homo sapiens 
2013-03-31 | E-GEOD-39182 | biostudies-arrayexpress
Genomicsena-DATASET-DKFZ-IBIOS-24-09-2015-14:57:59:343-450 - samples
release_2: ICGC PedBrain: whole exome sequencing and Target-Seq
EGAD00001001624 | EGA
Genomicsena-DATASET-DKFZ-IBIOS-24-09-2015-12:58:34:639-433 - samples
release_2: ICGC PedBrain: RNA sequencing
EGAD00001001620 | EGA
Genomicsena-DATASET-DKFZ-IBIOS-25-01-2016-08:42:37:641-84 - samples
Whole genome bisulfite sequencing of pedbrain - medulloblastoma
EGAD00001001891 | EGA
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