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MetabolomicsArsenic-induced enhancement of diazotrophic recruitment and nitrogen fixation in Pteris vittata rhizosphere
Heavy metal contamination poses an escalating global challenge to soil ecosystems. Hyperaccumulators play a crucial role in environmental remediation and resource recovery. The enrichment of diazotrophs and resulting nitrogen accumulation promoted hyperaccumulator growth and facilitated phytoremedia...
2024-11-01 | MTBLS11419 | MetaboLights
MetabolomicsMulti-omics dissection of Trametes versicolor CS05-mediated defense enhancement in Crocus sativus under Fusarium oxysporum corm rot stress

Saffron (Crocus sativus) is a high-value crop prized in culinary and pharmaceutical applications for its nutritional and therapeutic properties. However, corm rot caused by Fusarium oxysporum severely compromises yield and quality. Here, we isolated F. oxysporum strain CSP01 from diseased corms a...

2026-06-01 | MTBLS14647 | MetaboLights
TranscriptomicsAmitriptyline-mediated cognitive enhancement in aged 3xTg Alzheimer’s disease mice is associated with neurogenesis and neurotrophic activity
Approximately 35 million people worldwide suffer from Alzheimer’s disease (AD). Existing therapeutics, while moderately effective, are currently unable to stem the widespread rise in AD prevalence. AD is associated with an increase in amyloid beta (A) oligomers and hyperphosphorylated tau, along wit...
ORGANISM(S): Mus musculus 
2011-12-31 | E-GEOD-26836 | biostudies-arrayexpress
ProteomicsSerpina1e mediates the exercise-induced enhancement of hippocampal memory
Although exercise improves cognition, the specific molecules responsible for these beneficial effects remain unclear. Here, we propose that the myokine Serpina1e acts as a molecular mediator for these effects. Using an in vivo myokine-labeling mouse model, we confirmed that the Serpina1 family of pr...
ORGANISM(S): Mus musculus (Mouse) 
2026-06-15 | PXD055604 | Pride
Exercise Hippocampus Cognitive enhancement Serpina1e Skeletal muscle Memory Neurogenesis Bdnf Myokine 
TranscriptomicsCBP is required for environmental enrichment-induced neurogenesis and cognitive enhancement.
The epigenetic changes of the chromatin represent an attractive molecular substrate for adaptation to the environment. We examined here the role of CBP, a histone acetyltransferase involved in mental retardation, in the genesis and maintenance of long-lasting systemic and behavioral adaptations to e...
ORGANISM(S): Mus musculus 
2011-08-29 | E-GEOD-30880 | biostudies-arrayexpress
Proteomicsproteomic changes in aging rats treated with the cognitive enhancer CE-123
Aging rats with cognitive decline have been behaviourally evaluated and were divided into two groups, treated with CE-123, a dopamine transporter inhibitor, and vehicle. Memory-related brain areas were dissected and following sample preparation run on q-exactive from thermo fisher. Data handling and...
ORGANISM(S): Rattus norvegicus (Rat) 
2022-02-16 | PXD022737 | Pride
Brain Cognitive enhancement Rat Aging 
TranscriptomicsIdentification of circulation microRNAs correlated with human POCD development
The preoperative and 24h postoperative peripheral blood samples from 3 patients who were clinically diagnosed with POCD 7 days after surgery and who presented with an improvement of cognitive function 3 months later were used to a microRNA microarray analysis. The microarray results showed that, com...
ORGANISM(S): Homo sapiens 
2015-02-13 | E-MTAB-3187 | biostudies-arrayexpress
UnknownCognitive Enhancement via Network-Targeted Cortico-cortical Associative Brain Stimulation.
Not available
S-EPMC7132941 | biostudies-literature
UnknownCognitive enhancement with Salience Network electrical stimulation is influenced by network structural connectivity.
Not available
S-EPMC6299257 | biostudies-literature
UnknownParents' Perceptions on the Debated Parenting Practice of Cognitive Enhancement in Healthy Children and Adolescents.
Not available
S-EPMC9360129 | biostudies-literature
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