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TranscriptomicsProtein Kinase C Alpha Promotes Tumor Growth by Initiating a Feed-forward Network Involving miR-15a and Cyclin E
Protein Kinase C alpha (PKC) is associated with progression and poor prognosis in head and neck cancer. Previous studies have demonstrated that PKC sustains the proliferative signal by increasing cyclin E expression, leading to enhanced E2F target gene transcription and DNA synthesis. Here we show ...
ORGANISM(S): Homo sapiens 
2010-10-08 | E-GEOD-10301 | biostudies-arrayexpress
UnknownGenetic predictor of working memory and prefrontal function in women with HIV.
Not available
S-EPMC4319991 | biostudies-literature
UnknownCabozantinib in progressive medullary thyroid cancer.
Not available
S-EPMC4164813 | biostudies-literature
UnknownTrauma patients with type O blood exhibit unique multiomics signature with decreased lectin pathway of complement levels.
Not available
S-EPMC11502284 | biostudies-literature
UnknownEfficacy and safety of the biosimilar ABP 501 compared with adalimumab in patients with moderate to severe rheumatoid arthritis: a randomised, double-blind, phase III equivalence study.
Not available
S-EPMC5629940 | biostudies-literature
TranscriptomicsIntegrative genomic analysis identifies clinically relevant subtypes of head and neck cancer characterized by hypoxia, T-cell infiltration, and EMT
Current classification of head and neck squamous cell carcinomas (HNSCC) based on anatomic site and clinical stage fails to capture biologic heterogeneity or adequately inform treatment. Here we use consensus clustering on 371 HNSCC in three cohorts, including a new cohort of 134 patients with locor...
ORGANISM(S): Homo sapiens 
2015-03-04 | E-GEOD-40774 | biostudies-arrayexpress
TranscriptomicsGene expression data from 131 human subjects in Detroit, Michigan
Background Complex diseases are often difficult to diagnose, treat and study due to the multi-factorial nature of the underlying etiology. Large data sets are now widely available that can be used to define novel, mechanistically distinct disease subtypes (endotypes) in a completely data-driven mann...
ORGANISM(S): Homo sapiens 
2013-11-12 | E-GEOD-35571 | biostudies-arrayexpress
UnknownEpidemiology of carbapenem-resistant and carbapenemase-producing Enterobacterales in the Netherlands 2017-2019.
Not available
S-EPMC8994189 | biostudies-literature
UnknownA structured approach to integrating mental health services into primary care: development of the Mental Health Scale Up Nigeria intervention (mhSUN).
Not available
S-EPMC5870530 | biostudies-literature
UnknownCombined TP53 mutation/3p loss correlates with decreased radiosensitivity and increased matrix-metalloproteinase activity in head and neck carcinoma.
Not available
S-EPMC4427339 | biostudies-literature
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