Sort   by:  
 Page size 
ProteomicsAssembly of a nuclear lamin coil 2 fragment
Nuclear structure and function are governed by lamins, which are intermediate filaments mostly consisting of α-helices. Different lamin assembly models have been proposed based on low resolution or fragmented structures. However, their assembly mechanisms at the molecular level are poorly understood...
ORGANISM(S): Homo sapiens (Human) 
2025-12-15 | PXD014029 | Pride
Human Coil 2 Lamin Nuclear protein 
ProteomicsUSP8 maintains ESC stemness via deubiquitination of EPG5
The coiled-coil domain of EPG5 was synthesized as follows: Biotin-MNKNEAVSQQIHVLQKEVRQLQAE AAQ (from Beijing SciLight Biotechnology, LCC). 1 mg of this short peptide was incubated with ES cells lysates followed by immunoprecipitation with anti-biotin beads. The precipitates were extensively washed w...
ORGANISM(S): Mus musculus (Mouse) 
2019-02-25 | PXD012563 | Pride
I.e.mouse.escs.epg5.usp8.lc-msms 
TranscriptomicsExpression data from HT-1080 cells incubated or not in the presence of laminin111 coiled-coiled recombinant fragment (rLCC111)
Laminins are large heterotrimeric cross-shaped extracellular matrix (ECM) glycoproteins with terminal globular domains and a coiled-coil region. We have produced for the first time a recombinant laminin coiled-coil domain and studied the transcriptional profile of cells incubated in coiled-coil-coat...
ORGANISM(S): Homo sapiens 
2011-10-11 | E-GEOD-32896 | biostudies-arrayexpress
GenomicsInhibition of Rho-associated, coiled-coil-containing protein kinase 2 in murine podocytes
Inhibition of Rho-associated, coiled-coil-containing protein kinase 2 in murine podocytes
PRJNA1090039 | ENA
GenomicsFolding of cohesin's coiled coil is important for Scc2/4-induced association with chromosomes
Folding of cohesin's coiled coil is important for Scc2/4-induced association with chromosomes
PRJNA704282 | ENA
TranscriptomicsExpression data from HT-1080 cells incubated or not in the presence of laminin111 coiled-coiled recombinant fragment (rLCC111)
Laminins are large heterotrimeric cross-shaped extracellular matrix (ECM) glycoproteins with terminal globular domains and a coiled-coil region. We have produced for the first time a recombinant laminin coiled-coil domain and studied the transcriptional profile of cells incubated in coiled-coil-coat...
ORGANISM(S): Homo sapiens 
2011-10-12 | GSE32896 | GEO
GenomicsA 36-base hairpin within lncRNA DRAIC interacts with the IKKα coiled-coil domain, weakening the IKK complex and inhibiting NF-kappaB activation
A 36-base hairpin within lncRNA DRAIC interacts with the IKKα coiled-coil domain, weakening the IKK complex and inhibiting NF-kappaB activation
PRJNA1171344 | ENA
OtherA 36-base hairpin within lncRNA DRAIC interacts with the IKKα coiled-coil domain, weakening the IKK complex and inhibiting NF-kappaB activation
Long noncoding RNAs have diverse functions, but not enough is known about the molecular mechanisms underlying their cellular functions. The 1.7 kb long down-regulated non-coding RNA in cancers (DRAIC) slows tumor growth and inhibits the activation of the transcription factor NF-kappaB through intera...
ORGANISM(S): Homo sapiens 
2025-07-01 | GSE279192 | GEO
UnknownMolecular basis of coiled-coil formation.
Not available
S-EPMC1855353 | biostudies-literature
GenomicsEffects of depletion of Rho-associated, coiled-coil-containing protein kinase 2 in the kidney medullary tussue of murine model.
Effects of depletion of Rho-associated, coiled-coil-containing protein kinase 2 in the kidney medullary tussue of murine model.
PRJNA1031226 | ENA
Sort   by:  
 Page size