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Investigation of whole genome gene expression level changes in cultures of Polaromonas sp. JS666 grown on cDCE compared to the reference substrate glycolate. JS666 is the first organism isolated capable of coupling growth to the aerobic oxidation of the chlorinated solvent, cis-1,2-dichloroethene (c...
ORGANISM(S): Polaromonas sp. JS666 
Androgen deprivation is the mainstay of therapy for progressive prostate cancer. Despite initial and dramatic tumor inhibition, most men eventually fail therapy and die of metastatic castration-resistant (CR) disease. Here, we characterize the profound degree of genomic alteration found in CR tumors...
ORGANISM(S): Homo sapiens 
Investigation of whole genome gene expression differences between a full (four-gene) SlrV locus 1 deletion compared to the WT PittII strain. Removal of the four SlrV genes (aka macrophage survival factors : ?msf) results in a competetive defect with the WT strain in in vitro biofilms and in the oti...
ORGANISM(S): Haemophilus influenzae PittII 
Investigation of whole genome gene expression differences between a full (nine-gene) Lsr locus deletion and a luxS deletion strain (double knock-out) compared to a luxS isogenic mutant strain (each derived from the CZ4126/02 parent strain). Both strains are unable to produce the autoinducer-2 (AI-2)...
ORGANISM(S): Haemophilus influenzae 
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