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TranscriptomicsGenome-wide profiling of diel and circadian gene expression of the malaria vector Anopheles gambiae
Anopheles gambiae, the primary African malarial mosquito, exhibits numerous behaviors that are under diel and circadian control, including locomotor activity, swarming, mating, host seeking, eclosion, egg laying and sugar feeding. However, little has been performed to elucidate the molecular basis f...
ORGANISM(S): Anopheles gambiae 
2011-06-29 | E-GEOD-22585 | biostudies-arrayexpress
TranscriptomicsNotch targets in KC Drosophila cells
To identify genes upregulated in response to Notch signalling in KC cells. Keywords: Expression analysis at a single timepoint (30' after Notch activation) KC cells were obtained from Dr Martin Zeidler. Control versus Notch activated KC cells: mRNA was extracted from KC cells incubated in the absenc...
ORGANISM(S): Drosophila melanogaster 
2010-06-23 | E-GEOD-9965 | biostudies-arrayexpress
ProteomicsMedieval birth girdle stains LC-MSMS
This project applied a dry non-invasive method to detect palaeoproteomic evidence from stained manuscripts. The manuscript analysed in this study is a medieval parchment birth girdle (Wellcome Collection Western MS. 632) made in England and thought to be used by pregnant women while giving birth. Us...
ORGANISM(S): Pisum sativum (Garden pea) Homo sapiens (Human) Apis mellifera (Honeybee) Ovis aries Vicia faba 
2021-09-09 | PXD022054 | Pride
Medieval Birth Lc-msms 
TranscriptomicsMammalian PERIOD complex regulates repair of DSB in active chromatin through anchoring to the nuclear envelope
Repair of DNA Double Strand Breaks produced in transcriptionally active chromatin occurs through a mechanism, Transcription-Coupled DSB repair (TC-DSBR), that is yet poorly characterized. Here, using a screening approach scoring multiple outputs in human cells, we identified the PER complex, a key m...
ORGANISM(S): Homo sapiens 
2025-11-12 | E-MTAB-12712 | biostudies-arrayexpress
UnknownPhase I Study of Acalabrutinib Plus Danvatirsen (AZD9150) in Relapsed/Refractory Diffuse Large B-Cell Lymphoma Including Circulating Tumor DNA Biomarker Assessment.
Not available
S-EPMC10472096 | biostudies-literature
TranscriptomicsChIP-chip from Kc cells with Su(H) antibodies after 30 minutes Notch activation
During hematopoiesis, Notch regulates both the emergence of stem and progenitor cells and the subsequent cell fate choices and differentiation. To investigate how Notch drives cells to differentiate we have used a genome-wide approach to identify direct Notch targets in Drosophila Kc cells. These da...
ORGANISM(S): Drosophila melanogaster 
2013-03-08 | E-GEOD-43132 | biostudies-arrayexpress
GenomicsExome sequencing in classic Hairy cell leukaemia reveals widespread variation in acquired somatic mutations between individual tumours apart from the signature BRAF V(600)E lesion
Whole exome sequencing of 5 HCLc tumor-germline pairs. Genomic DNA from HCLc tumor cells and T-cells for germline was used. Whole exome enrichment was performed with either Agilent SureSelect (50Mb, samples S3G/T, S5G/T, S9G/T) or Roche Nimblegen (44.1Mb, samples S4G/T and S6G/T). The resulting exom...
ORGANISM(S): Homo sapiens 
2016-02-01 | E-MTAB-4313 | biostudies-arrayexpress
UnknownAZD8701, an Antisense Oligonucleotide Targeting FOXP3 mRNA, as Monotherapy and in Combination with Durvalumab: A Phase I Trial in Patients with Advanced Solid Tumors.
Not available
S-EPMC11995004 | biostudies-literature
UnknownEnasidenib in mutant <i>IDH2</i> relapsed or refractory acute myeloid leukemia.
Not available
S-EPMC5572791 | biostudies-literature
UnknownLipid-induced insulin resistance mediated by the proinflammatory receptor TLR4 requires saturated fatty acid-induced ceramide biosynthesis in mice.
Not available
S-EPMC3083776 | biostudies-literature
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