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MetabolomicsMultiomics and digital monitoring during lifestyle changes reveal independent dimensions of human biology and health

In order to explore opportunities for personalized and predictive health care, we collected serial clinical measurements, health surveys and multiomics profiles (genomics, proteomics, autoantibodies, metabolomics and gut microbiome) from 96 individuals. The participants underwent data-driven heal...

2021-09-02 | MTBLS2187 | MetaboLights
MetabolomicsComparative Lipidomics of Different Yeast Species Associated to Drosophila suzukii
Yeasts constitute a dietary source for the spotted wing drosophila (SWD) and produce compounds that attract these flies. The study of the chemical composition of the yeast communities associated with SWD should therefore help to understand the relationship between the biology of the insect and the y...
2021-02-05 | MTBLS1955 | MetaboLights
MetabolomicsComparative Analysis of Host Metabolic Alterations in Murine Malaria Models with Uncomplicated or Severe Malaria

Malaria varies in severity, with complications ranging from uncomplicated to severe malaria. Severe malaria could be attributed to peripheral hyperparasitemia or cerebral malaria. The metabolic interactions between the host and Plasmodium species are yet to be understood during these inf...

2022-09-14 | MTBLS4387 | MetaboLights
TranscriptomicsSupervised Lowess normalization of comparative genome hybridization data: application to lactococcal strain comparisons.
Background Array-based comparative genome hybridization (aCGH) is commonly used to determine the genomic content of bacterial strains. In aCGH data, systematic errors are comparable to those occurring in transcriptome data. However, especially for microbes, an additional source of variation exists: ...
ORGANISM(S): Lactococcus lactis subsp. cremoris MG1363 
2008-07-19 | E-GEOD-9039 | biostudies-arrayexpress
TranscriptomicsTranscription profiling by array on 123 paired tumor and non-tumor tissue samples from patients with non-small cell lung carcinoma to gain a systems biology insight into the current clinical classification
Non-small cell lung cancer (NSCLC), a leading cause of cancer deaths, represents a heterogeneous group of neoplasms, mostly comprising squamous cell carcinoma (SCC), adenocarcinoma (AC) and large-cell carcinoma (LCC). The aim of this study was to gain a systems biology insight into the current clini...
ORGANISM(S): Homo sapiens 
2013-12-11 | E-MTAB-1132 | biostudies-arrayexpress
GenomicsComparative genomics and genome biology of Campylobacter showae
Comparative genomics and genome biology of Campylobacter showae
PRJEB17707 | ENA
TranscriptomicsEstablishment and Comparative Characterization of Novel Non-Small Cell Lung Cancer Cell Lines and Their Corresponding Tumor Tissue
Cell lines play an important role for studying tumor biology and novel therapeutic agents. We demonstrated that cell lines represent a useful and reliable in vitro system for studying basic mechanisms in lung cancer. Moreover, we presented 3 novel, comprehensively characterized SCC cell lines. Estab...
ORGANISM(S): Homo sapiens 
2011-08-30 | E-GEOD-25251 | biostudies-arrayexpress
TranscriptomicsComparative transcriptome and network biology analyses demonstrate antiproliferative and hyperapoptotic phenotypes in human keratoconus corneas
Comparative transcriptome between Keratoconus and control corneas
ORGANISM(S): Homo sapiens 
2011-08-17 | E-MEXP-2777 | biostudies-arrayexpress
TranscriptomicsSystems Biology Analysis of Zymomonas mobilis ZM4 Ethanol Stress Responses
Background Zymomonas mobilis ZM4 is a capable ethanologenic bacterium with high ethanol productivity and ethanol tolerance. Previous studies indicated that several stress-related proteins and changes in the ZM4 membrane lipid composition may contribute to ethanol tolerance. However, the molecular m...
ORGANISM(S): Zymomonas mobilis subsp. mobilis ZM4 = ATCC 31821 
2013-09-04 | E-GEOD-21165 | biostudies-arrayexpress
TranscriptomicsPhysical mapping of genes in somatic cell radiation hybrids by comparative genomic hybridization to cDNA microarrays
Somatic cell mutants can be informative in the analysis of a wide variety of cellular processes. The use of map- based positional cloning strategies in somatic cell hybrids to analyze genes responsible for recessive mutant phenotypes is often tedious, however, and remains a major obstacle in somatic...
ORGANISM(S): Homo sapiens 
2005-09-09 | E-GEOD-3269 | biostudies-arrayexpress
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