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MetabolomicsConsistency across multi-omics layers in a drug-perturbed gut microbial community
Multi-omics analyses are increasingly employed in microbiome studies to obtain a holistic view of molecular changes occurring within microbial communities exposed to different conditions. However, it is not always clear to what extent each omics data type contributes to our understanding of the comm...
2022-12-08 | MTBLS3129 | MetaboLights
MetabolomicsIntra-tumoral microbial community profiling and associated metabolites alterations of TNBC

Triple-negative breast cancer (TNBC) presents significant challenges to female

health owing to the lack of therapeutic targets and its poor prognosis. In recent

years, in the field of molecular pathology, there has been a growing focus on the

role of intra-tumoral microbial comm...

2025-10-12 | MTBLS13119 | MetaboLights
MetabolomicsPlant hosts modify belowground microbial community response to extreme drought

Drought stress negatively impacts microbial activity, but the magnitude of stress responses are likely dependent on a diversity of below ground interactions. Populus trichocarpa individuals and no plant bulk soils were exposed to extended drought (~0.03% gravimetric water content (GWC) after 12d)...

2020-06-19 | MTBLS1463 | MetaboLights
MetabolomicsArtificial fermentation with trichome exudate improves microbial community composition and leaf quality in cigar tobacco
Diterpenoids and sucrose esters are synthesized in cigar tobacco leave (CTLs) trichomes and secreted onto leaf surface as trichome exudate (TE), contributing to sensory quality.To reveal the mechanism by which TE affects CTLs quality, this study employed the half-leaf method, utilizing tobacco extra...
2026-06-17 | MTBLS14776 | MetaboLights
MetabolomicsCommunity metabolomics provides insights into mechanisms of pollution-induced community tolerance of periphyton

Chemical pollution is a major concern for freshwater ecosystems, but the impact and mechanisms of chemical stressors on communities are barely understood. Pollution stress beyond natural homeostatic capacities can trigger succession of tolerant species within a community, enhancing the overall co...

2022-02-11 | MTBLS3595 | MetaboLights
MetabolomicsMetabolic network construction reveals probiotic-specific colonization resistance in a synthetic small intestinal community

The gut microbiota is essential to host health. Probiotics can be used as a microbiota targeted therapy to improve host health. However, probiotic molecular mechanisms of action and probiotics targeting the small intestinal microbiota are often not elucidated. In this study, we construct a three ...

2024-09-26 | MTBLS7370 | MetaboLights
ProteomicsProteome data on soil microbial community
Soil microbial community is a complex blackbox that requires a multi-conceptual approach (Hultman et al., 2015; Bastida et al., 2016). Most methods focus on evaluating total microbial community and fail to determine its active fraction (Blagodatskaya & Kuzyakov 2013). This issue has ecological conse...
ORGANISM(S): Escherichia coli 
2021-02-02 | PXD005447 | Pride
Metaproteomics Soil Microbial community 
MetabolomicsRS5-lycopene complex alleviates diabetic glycogen fragility

This study demonstrates for the first time that CS-LYC, an RS5-based starch-lycopene complex, alleviates T2DM via gut microbiota-mediated regulation, providing novel evidence supporting starch-based functional foods in T2DM management.

2026-02-05 | MTBLS13849 | MetaboLights
ProteomicsNitrogen competition and proteome allocation in a surface-ocean microbial community
Dataset from a shipboard incubation experiment of an ocean surface-water microbial community sampled at 25m depth at Station ALOHA in the North Pacific Subtropical Gyre. Incubations were amended with ammonium, glutamate, leucine, nitrate and urea, in two isotopic variants: 15N (to track incorporatio...
ORGANISM(S): Microbial Community From North Pacific Ocean Surface Water 
2022-03-23 | MSV000089118 | MassIVE
MetabolomicsAdaptive laboratory evolution of microbial co-cultures for improved metabolite secretion

Adaptive laboratory evolution has proven highly effective for obtaining microorganisms with enhanced capabilities. Yet, this method is inherently restricted to the traits that are positively linked to cell fitness, such as nutrient utilization. Here, we introduce coevolution of obligatory mutuali...

2021-07-02 | MTBLS2217 | MetaboLights
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