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TranscriptomicsSmall RNAs in four Argonaute complexes in Arabidopsis
The core components of RNA silencing effector complexes include small RNAs and members of the Argonaute (AGO) protein family. Arabidopsis encodes ten AGOs and complex population of small RNAs. It remains largely unknown how these small RNAs are recognized and recruited by each AGO complex. Here we p...
ORGANISM(S): Arabidopsis thaliana 
2008-04-05 | E-GEOD-10036 | biostudies-arrayexpress
TranscriptomicsPyrococcus furiosus crRNAs associated with Cmr, Csa and Cst CRISPR-Cas systems
CRISPR-Cas immune systems function to defend prokaryotes against potentially harmful mobile genetic elements including viruses and plasmids. The multiple CRISPR-Cas systems (Types I, II, III) each recognize and target destruction of foreign invader nucleic acids via structurally and functionally div...
ORGANISM(S): Pyrococcus furiosus 
2015-07-10 | E-GEOD-65781 | biostudies-arrayexpress
TranscriptomicsProfiling of small RNA populations in rice total extract and purified AGO1 complexes
microRNAs (miRNAs) are a class of small silencing RNAs that have regulatory roles in gene expression. miRNAs interact with Argonaute (AGO) proteins to form effector complexes that can cleave target mRNAs or repress their translation. Rice encodes four AGO1 homologs (AGO1a, AGO1b, AGO1c, and AGO1d). ...
ORGANISM(S): Oryza sativa 
2009-11-23 | E-GEOD-18250 | biostudies-arrayexpress
TranscriptomicsIdentification of small RNAs in rice AGO1 complexes and their targets
This SuperSeries is composed of the following subset Series: GSE18248: Sequencing of rice degradome GSE18250: Profiling of small RNA populations in rice total extract and purified AGO1 complexes Refer to individual Series
ORGANISM(S): Oryza sativa 
2009-11-23 | E-GEOD-18251 | biostudies-arrayexpress
ProteomicsProteomic Mapping of multifunctional complexes in triatomine Saliva
Salivary multiprotein complexes from Triatoma infestans, Triatoma dimidiata, Dipetalogaster maxima, Rhodnius prolixus, and Rhodnius neglectus were identified by Blue-Native-PAGE (BN-PAGE) coupled with liquid chromatography tandem mass spectrometry.
ORGANISM(S): Triatominae (ncbitaxon:70999) 
2020-03-18 | MSV000085118 | MassIVE
GenomicsH2A.Z Facilitates Access of Active and Repressive Complexes to Chromatin in Embryonic Stem Cell Self-renewal and Differentiation
Chromatin modifications have been implicated in the self-renewal and differentiation of embryonic stem cells (ESCs). However, the function of histone variant H2A.Z in ESCs remains unclear. We show that H2A.Z is highly enriched at promoters and enhancers and is required for both efficient self-renewa...
ORGANISM(S): Mus musculus 
2012-12-20 | E-GEOD-34483 | biostudies-arrayexpress
ModelsDorvash2019 - Dynamic modeling of signal transduction by mTOR complexes in cancer
This model is based on: Dynamic modeling of signal transduction by mTOR complexes in cancer Author: Mohammadreza Dorvash, Mohammad Farahmandnia, Pouria Mosaddeghi, Mitra Farahmandnejad, Hosein Saber, Mohammadhossein Khorraminejad-Shirazi, Amir Azadi, Iman Tavassoly Abstract: Signal integration has...
2024-09-02 | BIOMD0000000822 | BioModels
GenomicsPCGF Homologs and RYBP Define Functionally Distinct PRC1 Family Complexes
The heterogeneous nature of mammalian PRC1 complexes has hindered our understanding of their biological functions. Here, we present a comprehensive proteomic and genomic analysis that uncovered six major groups of PRC1 complexes each containing a distinct PCGF subunit, a RING1A/B ubiquitin ligase, a...
ORGANISM(S): Homo sapiens 
2012-02-09 | E-GEOD-34774 | biostudies-arrayexpress
GenomicsSS18-SSX-mediated hijacking of BAF complexes drives synovial sarcoma
Synovial sarcoma (SS) is defined by a recurrent t(x;18) chromosomal translocation, which produces the hallmark SS18-SSX oncogenic fusion. Incorporation of SS18-SSX into BAF complexes renders BAF complexes aberrant in two distinct manners: the addition of 78aa of SSX onto SS18, and concomitant loss o...
EGAS00001002920 | EGA
TranscriptomicsANGUSTIFOLIA 3 binds SWI/SNF chromatin remodeling complexes to regulate transcription during Arabidopsis leaf development
The transcriptional coactivator ANGUSTIFOLIA 3 (AN3) stimulates cell proliferation during Arabidopsis leaf development, but the molecular mechanism is largely unknown. We show here that inducible nuclear localization of AN3 during initial leaf growth results in differential expression of important t...
ORGANISM(S): Arabidopsis thaliana 
2014-09-09 | E-GEOD-42875 | biostudies-arrayexpress
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