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Discovery of therapies that are able to correct defective CFTR requires patient derived in vitro pre-clinical cell models to be developed. Two main approaches exist to expand bronchial and nasal cultures, such as conditionally reprogrammed cells (CRC) and feeder free dual SMAD inhibition (SMADi) to ...
ORGANISM(S): Homo sapiens (Human) 
2021-12-05 | PXD018386 | Pride
RNA sequence data for conditionally reprogrammed cells from patient HUB_5
Conditionally reprogrammed cells from patient-derived xenograft to model neuroendocrine prostate cancer development
Establishing 3D Organoid Models from Patient-Derived Conditionally Reprogrammed Cells to Bridge Preclinical and Clinical Insights in Pancreatic Cancer
RNA seq data was used for the characterization and profiling of the created patient-derived cells and in vivo tissue.
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