Conjugate - OmicsDI

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UNIPROT ID/AC

3HAO_YEAST (1)
6PGD1_YEAST (1)
AAP1_YEAST (1)
AATC_YEAST (1)
AB140_YEAST (1)
ABF2_YEAST (1)
ABP1_YEAST (1)
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ALDH2_YEAST (1)
ALDH4_YEAST (1)
ALDH6_YEAST (1)
ALF_YEAST (1)
ALO_YEAST (1)
AMPD_YEAST (1)

CHEBI ID

CHEBI:189652 (1)
CHEBI:73676 (1)
CHEBI:149460 (1)
CHEBI:149457 (1)
CHEBI:149459 (1)
CHEBI:149450 (1)
CHEBI:149447 (1)
CHEBI:149456 (1)
CHEBI:149454 (1)
CHEBI:149452 (1)
CHEBI:149449 (1)
CHEBI:149442 (1)
CHEBI:17639 (1)
CHEBI:67408 (1)
CHEBI:142436 (1)
CHEBI:142428 (1)
CHEBI:142427 (1)
CHEBI:75489 (1)
CHEBI:142426 (1)
CHEBI:88097 (1)
CHEBI:43419 (1)
CHEBI:16628 (1)
CHEBI:82679 (1)
CHEBI:32636 (1)
CHEBI:10022 (1)
CHEBI:18319 (1)
CHEBI:88000 (1)
CHEBI:90168 (1)
CHEBI:77064 (1)
CHEBI:16325 (1)

Metabolite Name

Metab_0 (1)
Mz1 (1)
3-oxo-5beta-cholan-24-oic-acid (1)
7alpha-Hydroxy-5beta-cholan-24-oic acid (1)
Lithocholic acid (LCA) (1)
7-oxo-lithocholic acid (7-oxoLCA) (1)
3-oxo-chenodeoxycholic acid (3-oxoCDCA) (1)
Isoursochenodexycholic acid (iUDCA) (1)
Chenodeoxycholic acid (CDCA) (1)
Rac-N,N-Didesmethyl-O-desmethylvenlafaxine glucuronide (1)
P-Acetamidophenyl .beta.-D-glucuronide (1)
All-trans-4-Ketoretinoic acid (1)
Valproic acid .beta.-D-glucuronide (1)
Uridine-5'-diphospho-n-acetylgalactosamine (1)
Uridine 5'-diphosphoglucuronic acid (1)
Udp-beta-l-rhamnose (1)
Trifucosyllacto-N-hexaose (1)
Trans-zeatin-riboside (1)
Trans-dehydroandrosterone (1)
Sulfocholic acid (1)
Soyasapogenol b base + o-hexa-pen-dhex (1)
Soyasapogenol b base + o-hexa-hex (1)
Solasodine base + 2h, o-hex-hex-hex-pen (1)
Slca - sulfolithocholic acid (1)
Sinalbin (1)
Salicylic acid .beta.-D-O-glucuronide (1)
Rosmic acid (1)
Rebaudioside e (1)
Rapamycin (1)
Prostaglandin F3.alpha. (1)

First Public Date

2026 (59)
2025 (53)
2024 (39)
2014 (22)
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2021 (21)
2022 (17)
2018 (11)
2017 (11)
2020 (10)
2015 (6)
2016 (5)
2019 (4)
2013 (4)
2012 (2)
2011 (1)
2010 (1)

Modelling Approach

Markov model (1)
Ordinary differential equation model (1)

Study status

Not provided (2)
Terminated (1)
Active, not recruiting (1)
Completed (1)

Lab affiliation

ETH Zurich (3)
CECAD, University of Cologne (2)
Daegu Catholic University School of Medicine (2)
ETH Zurich, Institute of Molecular Systems Biology, Zurich, Switzerland (2)
Massachusetts Institute of Technology, Department of Biological Engineering, David H Koch Institute for Integrative Cancer Research (2)
Molecular Cell and Developmental Biology, School of Life Sciences, University of Dundee, United Kingdom (2)
Robarts Research Institute, Department of Biochemistry,Schulich School of Medicine & Dentistry, The University of Western Ontario, London, Ontario, Canada, N6A 5B7 (2)
Shanghai Key Laboratory of Bioactive Small Molecules, Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Fudan University Shanghai Medical College, Shanghai 200032, China. (2)
The Walter and Eliza Hall Institute (2)
1 Medical Research Council (MRC) Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences, University of Dundee (1)
1) Chemical Biology Program, Memorial Sloan Kettering Cancer Center, New York, New York, 10065, USA. 2) Pharmacology Program of the Weill Cornell Graduate School of Medical Sciences, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA. 3) Tri-Institutional PhD Program in Chemical Biology, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA. (1)
1. Center for Medical Biotechnology, VIB, Ghent, Belgium 2. Department for Biomolecular Medicine, Ghent University, Ghent, Belgium 3. VIB Proteomics Core, VIB, Ghent, Belgium (1)
1. Center for Medical Biotechnology, VIB, Ghent, Belgium. 2. Department for Biomolecular Medicine, Ghent University, Ghent, Belgium 3. VIB Proteomics Core, VIB, Ghent, Belgium (1)
1. Institute of Chemical Biology, Shenzhen Bay Laboratory, 518107 Shenzhen, China; 2. School of Chemical Biology and Biotechnology, Peking University Shenzhen Graduate School, Shenzhen 518055, China (1)
1. Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR), 8A Biomedical Grove, Immunos, Singapore 138648, Republic of Singapore 2. Department of Pharmacy, National University of Singapore 3. Biomolecular Mass Spectrometry and Proteomics, Bijvoet Center for Biomolecular Research and Utrecht Institute for Pharmaceutical Sciences, Utrecht University, 3584 CH Utrecht, the Netherlands (1)
2. Wellcome MRC Cambridge Stem Cell Institute, University of Cambridge, Cambridge, UK (1)
6Department of Molecular Science/UT Health Rio Grande Valley, USA (1)
Aarhus University Department of Biomedicine Høegh-Guldbergsgade 10 DK-8000 Aarhus C (1)
Aging and Cardiovascular Discovery Center, Lewis Katz School of Medicine, Temple University, Philadelphia, PA 19140, USA (1)
Allergy Research Group, Instituto de Investigación Biomédica de Málaga-IBIMA, Málaga, Spain (1)
BGI-Shenzhen, Shenzhen, 518083,China (1)
Biomolecular Mass Spectrometry & Proteomics, Bijvoet Center for Biomolecular Research & Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Padualaan 8, 3584 CH Utrecht, The Netherlands.; Netherlands Proteomics Center, Padualaan 8, 3584 CH Utrecht, The Netherlands (1)
Biomolecular Mass Spectrometry and Proteomics Bijvoet Center for Biomolecular Research and Utrecht Institute for Pharmaceutical Sciences Utrecht University (1)
Biomolecular Mass Spectrometry and Proteomics, Bijvoet Center for Biomolecular Research and Utrecht Institute for Pharmaceutical Sciences, University of Utrecht, Padualaan 8, Utrecht 3584 CH The Netherlands Netherlands Proteomics Center, Padualaan 8, Utrecht 3584 CH, The Netherlands (1)
CNRS, University of Strasbourg, UMR7242, UMR7242, ESBS, Bld Sébastien Brant, F-67412 Illkirch, Strasbourg, France. University of Strasbourg, UMR7242, ESBS, Bld Sébastien Brant, F-67412 Illkirch, Strasbourg, France. (1)
Carnegie MS Facility (1)
Center for Cell Lineage and Development, CAS Key Laboratory of Regenerative Biology, Guangdong Provincial Key Laboratory of Stem Cell and Regenerative Medicine, GIBH-HKU Guangdong-Hong Kong Stem Cell and Regenerative Medicine Research Centre, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China. (1)
Center for Integrated Protein Science at the Department of Chemistry, Technische Universität München, Garching b. München 85747, Germany; Chair of Organic Chemistry II, Technische Universität München, Garching b. München 85747, Germany (1)
Center for Proteomics and Metabolomics, Leiden Universtity Medical Center, The Netherlands (1)
Center for Reproductive Evolution, Biology Department, Syracuse University, Syracuse, NY, 13244, USA (1)

Keyword

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Classification

bacteria (16)
protozoa (1)

Study type

Transcription profiling by array (383)
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RNA-seq of coding RNA (20)
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ChIP-chip by array (9)
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Location

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United States (2)
China (1)

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Transcription profiling of the human K562 cell line treated with the polyamide-Chl conjugate 1R-Chl

To determine whether the polyamide-Chl conjugate 1R-Chl would cause similar changes in global gene expression in K562 cells, affymetrix gene chip analysis was performed using 1R-Chl. Through class comparison analysis, 1R-Chl affected the levels of transcription and genes of interest were determined...

ORGANISM(S): Homo sapiens

2008-06-16 | E-GEOD-8832 | biostudies-arrayexpress

Synergistic Effect of a Mesothelin-Targeted ²²⁷Th Conjugate in Combination with DNA Damage Response Inhibitors in Ovarian Cancer Xenograft Models.

Not available

S-EPMC6735281 | biostudies-literature

Targeted alpha therapy using a novel CD70 targeted thorium-227 conjugate in in vitro and in vivo models of renal cell carcinoma.

Not available

S-EPMC5593563 | biostudies-literature

Proteomics analysis of the molecular mechanism by which Antibody-drug conjugate Oba01 combined with Abemaciclib kills colorectal cancer organoids

Proteomics reveals the molecular mechanism by which the antibody-drug conjugate Oba01 and the CDK4/6 inhibitor Abemaciclib jointly kill colorectal cancer organoids

ORGANISM(S): Homo Sapiens (human)

2025-05-03 | PXD063571 | JPOST Repository

Albumin-binding RNAi Conjugate for Carrier Free Treatment of Arthritis

PRJNA977646 | ENA

Enterobactin conjugate vaccine

PRJNA901477 | ENA

A Targeted Thorium-227 Conjugate Demonstrates Efficacy in Preclinical Models of Acquired Drug Resistance and Combination Potential with Chemotherapeutics and Antiangiogenic Therapies.

Not available

S-EPMC10477831 | biostudies-literature

Synergistic Effect of a HER2 Targeted Thorium-227 Conjugate in Combination with Olaparib in a BRCA2 Deficient Xenograft Model.

Not available

S-EPMC6958469 | biostudies-literature

Gene expression signatures for Hib conjugate vaccine

To development of our gene expression, we have employed whole rhesus monkey genome microarray expression profiling as a discovery platform to identify genes with the potential to induce immune response. The peripheral blood from rhesus macaques, who were immunized in groups of three with the capsula...

ORGANISM(S): Macaca mulatta

2016-11-24 | GSE90481 | GEO

An antibody drug conjugate-like agent DTLL sensitizes gemcitabine-sensitive/resistant pancreatic cancer on basis of SMAD4 profiles

Chemoresistance to gemcitabine limits its clinical implementation for pancreatic ductal adenocarcinoma (PDAC). We previously generated an antibody drug conjugate (ADC) -like agent, EGFR/HER2 dual-targeting ligand-based lidamycin (DTLL), and studied the effect of DTLL combined with gemcitabine and th...

ORGANISM(S): Homo Sapiens

2022-03-02 | PXD031977 |

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