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Insulin resistance is a heterogeneous disorder caused by a range of genetic and environmental factors, and we hypothesise that its aetiology varies considerably between individuals. This heterogeneity provides significant challenges to the development of effective therapeutic regimes for long-term m...
ORGANISM(S): Mus musculus 
Transcriptional responses of an unencapsulated Streptococcus pneumoniae strain derived from TIGR4 to human macrophages THP-1 were investigated at the early stages of interactions (0.5 h, 1 h and 3h).
ORGANISM(S): Streptococcus pneumoniae 
The objective of this study was to determine the gene expression changes mediated by the alpha6beta4 integrin using MDA-MB-435 breast carcinoma cell line under normal culturing conditions (10% FCS in DMEM). Experiment Overall Design: Comparison of clones of MDA-MB-435 cells transfected with the inte...
ORGANISM(S): Homo sapiens 
Transcriptional changes of an TCS08 mutant (disrupted in rr08) compared to the parent wild-type strain TIGR4 when both strains were cultured to early logarithmic growth phase in THY broth.
ORGANISM(S): Streptococcus pneumoniae 
Here we describe the initial analysis of copy number variations in cattle selected for resistance or susceptibility to intestinal nematodes The custom aCGH chips that interrogated the whole genome CNVs were build for 3 pairs of contemporary parasite-susceptible and resistant Angus.
ORGANISM(S): Bos taurus 
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