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In this study, the effects of the contact allergens BQ, DNCB, NBB, Ni, and PPD were investigated in THP-1 cells. For this purpose, LFQ- and SILAC-based untargeted proteomics were applied.
ORGANISM(S): Homo sapiens (Human) 
2023-09-13 | PXD031017 | Pride
Allergic and irritant contact dermatitis induces different immunological cascades, involving a plethora of immune cells as well as keratinocytes. This highly interwoven network is regulated by miRNAs. However, which miRNAs are involved during allergic- and irritant-induced contact dermatitis is not ...
ORGANISM(S): Homo sapiens 
Allergic and irritant contact dermatitis induces different immunological cascades, involving a plethora of immune cells as well as keratinocytes. This highly interwoven network is regulated by miRNAs. However, which miRNAs are involved during allergic- and irritant-induced contact dermatitis is not ...
ORGANISM(S): Homo sapiens 
We aimed to characterize transcriptomic changes over time (baseline, 2 hours, 48 hours and 96 hours) after nickel-induced contact dermatitis in 6 human probands. As a contrast, 7 patients with SLS-induced irritant contact dermatitis were included. Therefore, the patch tests were applied onto the bac...
ORGANISM(S): Homo sapiens 
Allergic and irritant contact dermatitis induces different immunological cascades, involving a plethora of immune cells as well as keratinocytes. 96 patients were investigated using mRNA microarray experiments, of which 88 passed our QC criteria. Patients were topically exposed to allergens (nickel ...
ORGANISM(S): Homo sapiens 
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