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MetabolomicsUntargeted LC-HRMS Based-Plasma Metabolomics Reveals 3-O-Methyldopa as a New Biomarker of Poor Prognosis in High-Risk Neuroblastoma
Neuroblastoma (NB) is the most common extracranial malignant tumor in children. Although the survival rate of NB has improved over the years, the outcome of NB still remains poor for over 30% of cases. A more accurate risk stratification remains a key point in the study of NB and the availability of...
2023-07-14 | MTBLS4294 | MetaboLights
TranscriptomicsmiR-146a promotes the initiation and progression of melanoma by activating Notch signaling
Oncogenic mutations in BRAF and NRAS occur in 70% of melanomas. Here we identify a microRNA, miR-146a, that is highly upregulated by oncogenic BRAF and NRAS. Expression of miR-146a increases the ability of human melanoma cells to proliferate in culture and form tumors in mice, whereas knockdown of m...
ORGANISM(S): Homo sapiens 
2014-02-18 | E-GEOD-39983 | biostudies-arrayexpress
UnknownRacemization Pathway for MoO2(acac)2 Favored over Ray-Dutt, Bailar, and Conte-Hippler Twists.
Not available
S-EPMC9516665 | biostudies-literature
UnknownGut Microbiota-Produced Tryptamine Activates an Epithelial G-Protein-Coupled Receptor to Increase Colonic Secretion.
Not available
S-EPMC6055526 | biostudies-literature
TranscriptomicsmiR-146a promotes the initiation and progression of melanoma by activating Notch signaling
Oncogenic mutations in BRAF and NRAS occur in 70% of melanomas. Here we identify a microRNA, miR-146a, that is highly upregulated by oncogenic BRAF and NRAS. Expression of miR-146a increases the ability of human melanoma cells to proliferate in culture and form tumors in mice, whereas knockdown of m...
ORGANISM(S): Homo sapiens 
2014-02-18 | E-GEOD-39294 | biostudies-arrayexpress
UnknownAn easy and efficient method for native and immunoreactive Echinococcus granulosus antigen 5 enrichment from hydatid cyst fluid.
Not available
S-EPMC4132071 | biostudies-literature
UnknownMultidisciplinary study of a new ClC-1 mutation causing myotonia congenita: a paradigm to understand and treat ion channelopathies.
Not available
S-EPMC5024700 | biostudies-literature
UnknownHDAC class I inhibitor domatinostat sensitizes pancreatic cancer to chemotherapy by targeting cancer stem cell compartment via FOXM1 modulation.
Not available
S-EPMC8892808 | biostudies-literature
ProteomicsProteomic changes in the milk of water buffalo (Bubalus bubalis) with intramammary infection by Staphylococcus aureus and by non-aureus staphylococciProteomic changes in the milk of water buffalo (Bubalus bubalis) with intramammary infection by Staphylococcus aureus and by non-aureus staphylococci
The study reports a differential proteomic analysis of the Mediterranean buffalo milk to evaluate the changes induced by Staphylococcus spp. during a subclinical intramammary infection (IMI). A number of 12 quarter milk samples, 6 of which with somatic cell count (SCC) < 50,000 cells/mL and culture-...
ORGANISM(S): Bubalus bubalis 
2019-10-22 | PXD012355 | Pride
Mastitis Buffalo milk Label-free proteomics Lc-ms/ms 
UnknownDisulfide-activated protein kinase G Iα regulates cardiac diastolic relaxation and fine-tunes the Frank-Starling response.
Not available
S-EPMC5095173 | biostudies-literature
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