Sort   by:  
 Page size 
ProteomicsComposite SMG5-1 SMG6 PIN domain formation is essential for NMD
Nonsense-mediated mRNA decay (NMD) relies on the coordinated assembly and action of multiple protein factors. Degradation of target mRNAs begins with endonucleolytic cleavage near premature stop codons, but the mechanisms of endonuclease activation and regulation remain unclear. Using structural pre...
ORGANISM(S): Homo sapiens (Human) 
2026-01-30 | PXD072588 | Pride
Nonsense-mediated mrna decay 
ProteomicsXL-MS of RBBP6-bound CPSF complex
The 3’ ends of almost all eukaryotic mRNAs are generated in an essential two-step processing reaction, endonucleolytic cleavage of an extended precursor followed by the addition of a poly(A) tail. By reconstituting the reaction from overproduced and purified proteins, we provide a minimal list of fo...
ORGANISM(S): Homo sapiens (Human) 
2022-03-07 | PXD031242 | Pride
Cpa 3' end Cpsf 
ProteomicsProtein content and proximity map of yeast nuclear mRNPs
We isolated nuclear mRNPs from yeast using an endogenous bi-molecular tagging approach on Sub2 and Hpr1.
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2023-07-25 | PXD040736 | Pride
Cross-linking mass spectrometry (xl-ms) Mrna synthesis Mrnp assembly Rna annealing Ribonucleoprotein particles 
UnknownPrevalence, risk perception, and motivations behind E-cigarettes and heated tobacco use: a cross-sectional study in Italian adolescents.
Not available
S-EPMC12625768 | biostudies-literature
UnknownMetabolic Determinants and Anthropometric Indicators Impact Clinical-pathological Features in Epithelial Ovarian Cancer Patients.
Not available
S-EPMC4780127 | biostudies-literature
UnknownPrecision diagnostics of Ewing's sarcoma by liquid biopsy: circulating EWS-FLI1 fusion transcripts.
Not available
S-EPMC5985603 | biostudies-literature
UnknownPerioperative changes in pro and anticoagulant factors in prostate cancer patients undergoing laparoscopic and robotic radical prostatectomy with different anaesthetic techniques.
Not available
S-EPMC4431486 | biostudies-literature
UnknownGathering Novel Circulating Exosomal microRNA in Osteosarcoma Cell Lines and Possible Implications for the Disease.
Not available
S-EPMC6966608 | biostudies-literature
UnknownTissue factor as a potential coagulative/vascular marker in relapsing-remitting multiple sclerosis.
Not available
S-EPMC10424925 | biostudies-literature
UnknownCirculating cell-free DNA content as blood based biomarker in endometrial cancer.
Not available
S-EPMC5777767 | biostudies-literature
Sort   by:  
 Page size