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TranscriptomicsRelationship of mammographic density and gene expression: analysis of normal breast tissue surrounding breast cancer
Purpose: Previous studies of breast tissue gene expression have demonstrated that the extratumoral microenvironment has substantial variability across individuals, some of which can be attributed to epidemiologic factors. To evaluate how mammographic density (MD) and breast tissue composition relat...
ORGANISM(S): Homo sapiens 
2013-10-21 | E-GEOD-49175 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human breast cancers reveals bisphenol A induces a profile of tumor aggressiveness in high-risk cells of breast cancer patients
Breast cancer outcome is highly variable. Whether inadvertent exposure to environmental xenobiotics evokes a biological response promoting cancer aggressiveness and a higher probability of tumor recurrence remains unknown. To determine specific molecular alterations, which arise in high-risk breast ...
ORGANISM(S): Homo sapiens 
2008-06-11 | E-GEOD-10270 | biostudies-arrayexpress
TranscriptomicsLipid metabolism genes in contralateral unaffected breast and estrogen receptor status of breast cancer
The contralateral unaffected breast of women with unilateral breast cancer (cases) is a good model for defining subtype-specific risk since women with ER-negative index primaries are at high risk for subsequent ER-negative primary cancers. We performed random fine needle aspiration (rFNA) of the una...
ORGANISM(S): Homo sapiens 
2013-03-26 | E-GEOD-41400 | biostudies-arrayexpress
GenomicsDNA methylation patterns in breast cancer, paired benign tissue from ipsilateral and contralateral breast, and healthy controls
DNA methylation patterns in breast cancer, paired benign tissue from ipsilateral and contralateral breast, and healthy controls
PRJNA1212145 | ENA
ProteomicsHigh-throughput mass spectrometry and bioinformatics analysis of breast cancer proteomic data
The project contains raw and result files from a comparative proteomic analysis of malignant [primary breast tumor (PT) and axillary metastatic lymph nodes (LN)] and non-tumor [contralateral (NCT) and adjacent breast (ANT)] tissues of patients diagnosed with invasive ductal carcinoma. A label-free m...
ORGANISM(S): Homo sapiens (Human) 
2019-07-15 | PXD012431 | Pride
Proteomics Contralateral breast tissue Label-free mass spectrometry Breast cancer Bioinformatics analysis 
GenomicsEpigenetic field cancerization in breast cancer using subject-matched tumor, ipsilateral-normal, and contralateral-normal tissues
Epigenetic field cancerization in breast cancer using subject-matched tumor, ipsilateral-normal, and contralateral-normal tissues
PRJNA553244 | ENA
TranscriptomicsGene expression profiling in primary breast cancer distinguishes patients developing local recurrence after breast-conservation surgery, with or without postoperative radiotherapy.
Gene expression profiling of breast tumors for prognosis of local reccurence. Dual channel arrays with a tumor sample in one channel and a common reference in the other channel.
ORGANISM(S): Homo sapiens 
2011-09-02 | E-GEOD-31863 | biostudies-arrayexpress
Methylation profilingEpigenetic field cancerization in breast cancer using subject-matched tumor, ipsilateral-normal, and contralateral-normal tissues
Emerging work has demonstrated that histologically normal (non-tumor) tissue adjacent to breast tumor tissue shows evidence of molecular alterations related to tumorigenesis, referred to as field cancerization effects. Although changes in DNA methylation are known to occur early in breast carcinogen...
ORGANISM(S): Homo sapiens 
2020-07-10 | GSE133985 | GEO
TranscriptomicsTranscription profiling of human breast stroma and epithelium after curative radiotherapy to investigate the pathogenesis of late radiation injury in humans
Gene expression profiling of normal tissues after curative radiotherapy was carried out to investigate the pathogenesis of late radiation injury in humans. Irradiated and control normal breast tissue was collected from patients undergoing bilateral mastectomy for ipsilateral tumour relapse or proph...
ORGANISM(S): Homo sapiens 
2008-08-12 | E-TABM-419 | biostudies-arrayexpress
UnknownMRI background parenchymal enhancement, fibroglandular tissue, and mammographic breast density in patients with invasive lobular breast cancer on adjuvant endocrine hormonal treatment: associations with survival.
Not available
S-EPMC7441557 | biostudies-literature
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