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ProteomicsDetermining MELK inhibitor specificity using MIB/MS
The key objectives of this study were to evaluate the selectivity profiles of three MELK inhibitors, 8a, HTH, and OTS, using a cell-based assay, in order to identify a highly selective inhibitor to subsequently investigate MELK function. To this end, we utilized a chemical proteomics approach called...
ORGANISM(S): Homo sapiens (Human) 
2020-01-09 | PXD016022 | Pride
Chemoproteomics Lfq Kinase enrichment 
ProteomicsKinase Selectivity Profiling of anti-MRSA Diarylimidazoles in HEK293 Cells
Antimicrobial resistance (AMR) is widely acknowledged as one of the most serious public health threats facing the world, yet the private sector finds it challenging to generate much-needed medicines. As an alternative discovery approach, a small array of diarylimidazoles was screened against the ESK...
ORGANISM(S): Homo sapiens (Human) 
2024-01-26 | PXD040208 | Pride
Diarylimidazole Mib-ms Kinases Hek293 Antimicrobials 
UnknownRelationship between male pattern baldness and the risk of aggressive prostate cancer: an analysis of the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial.
Not available
S-EPMC4314593 | biostudies-literature
UnknownVIVA1: a more invasive subclone of MDA-MB-134VI invasive lobular carcinoma cells with increased metastatic potential in xenograft models.
Not available
S-EPMC9276762 | biostudies-literature
UnknownSafety and efficacy of immune checkpoint inhibitors (ICIs) in cancer patients with HIV, hepatitis B, or hepatitis C viral infection.
Not available
S-EPMC6918622 | biostudies-literature
UnknownWhole Genome Sequencing Differentiates Presumptive Extended Spectrum Beta-Lactamase Producing Escherichia coli along Segments of the One Health Continuum.
Not available
S-EPMC7143971 | biostudies-literature
UnknownGenomic Characterization of Enterococcus hirae From Beef Cattle Feedlots and Associated Environmental Continuum.
Not available
S-EPMC9271880 | biostudies-literature
UnknownMonospecific and bispecific monoclonal SARS-CoV-2 neutralizing antibodies that maintain potency against B.1.617.
Not available
S-EPMC8960874 | biostudies-literature
UnknownMonospecific and bispecific monoclonal SARS-CoV-2 neutralizing antibodies that maintain potency against B.1.617.
Not available
S-EPMC8722602 | biostudies-literature
UnknownDevelopment and validation of Burkholderia pseudomallei-specific real-time PCR assays for clinical, environmental or forensic detection applications.
Not available
S-EPMC3356290 | biostudies-literature
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