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TranscriptomicsCopy number profiling of PE ovarian cancer lines
The PEO/PEA series of ovarian cancer cell lines was established in 1988 from progressive samples from three separate cases of ovarian cancer (Langdon et al., 1988). Copy number profiling of PE lines on Illumina Infinium Human1M-Duo v3 BeadChips
ORGANISM(S): Homo sapiens 
2010-06-28 | E-GEOD-18461 | biostudies-arrayexpress
TranscriptomicsCopy number profiling of PEO1 ovarian cancer cell line
PEO1 is part of the PEO/PEA series of ovarian cancer cell lines established in 1988 from progressive samples from three separate cases of ovarian cancer (Langdon et al., 1988). Copy number profiling of PEO1 ovarian cancer cell line on Illumina HumanOmni1-Quad BeadChip
ORGANISM(S): Homo sapiens 
2011-06-30 | E-GEOD-29256 | biostudies-arrayexpress
TranscriptomicsCTCR-OV03/CTCR-OV04 ovarian cancer
High-grade serous ovarian cancer (HGSOC) exhibits significant genomic heterogeneity within a patient at presentation. Recent work has suggested that this heterogeneity is linked to the development of resistance and disease progression in that chemotherapy selects for minor resistant subclones embodi...
ORGANISM(S): Homo sapiens 
2014-10-01 | E-GEOD-40546 | biostudies-arrayexpress
TranscriptomicsDNA copy number data from the CE01 clinical study
Patients with cervical cancer were treated with external beam radiotherapy (EBRT) at a dose of 45Gy in 25 fractions over five weeks, with weekly cisplatin. Biopsies were taken pre-, during and post-treatment and analysed for copy number changes. Cervical cancer patients were treated with chemoradiot...
ORGANISM(S): Homo sapiens 
2010-10-25 | E-GEOD-21025 | biostudies-arrayexpress
TranscriptomicsArabidopsis defense against Botrytis cinerea: chronology and regulation deciphered by high-resolution temporal transcriptomic analysis (tga3-2 knockout data)
Transcriptional reprogramming forms a major part of a plant's response to pathogen infection. Many individual components and pathways operating during plant defense have been identified but our knowledge of how these different components interact is still rudimentary. We have generated a high-resolu...
ORGANISM(S): Arabidopsis thaliana 
2012-10-03 | E-GEOD-39597 | biostudies-arrayexpress
TranscriptomicsArabidopsis defense against Botrytis cinerea: chronology and regulation deciphered by high-resolution temporal transcriptomic analysis (time series)
A novel experimental design strategy (A Mead et al, in preparation), based on the principle of the M-bM-^@M-^\loop designM-bM-^@M-^], was developed to enable efficient extraction of information about key sample comparisons using a two-colour hybridisation experimental system. With 192 distinct sampl...
ORGANISM(S): Arabidopsis thaliana 
2012-10-02 | E-GEOD-29642 | biostudies-arrayexpress
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