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TranscriptomicsGlobal expression analysis identified a preferentially NGF-induced transcriptional program regulated by sustained MEK/ERK and AP-1 activation during PC12 differentiation.
Neuronal differentiation of PC12 cells in response to NGF is a prototypical model in which signal duration determines a biological response. Sustained ERK activity induced by NGF, as compared to transient activity induced by EGF, is critical to the differentiation of these cells. To characterize the...
ORGANISM(S): Rattus norvegicus 
2011-11-13 | E-GEOD-33639 | biostudies-arrayexpress
GenomicsWhole genome sequences of four novel bacteria species isolated from clinical samples from men assessed for Prostate Cancer
Isolation and characterisation of four novel species of anaerobic bacteria isolated from urine and prostate samples from men assessed for prostate cancer.
PRJEB40417 | ENA
GenomicsEGAS00001000262-sc-20131030 - samples
Whole genome DNA sequencing was used to decrypt the phylogeny of multiple samples from distinct areas of cancer and morphologically normal tissue taken from the prostates of 3 men. For each of three different prostates, multiple tumour samples (4, 5, and 3 depending on the case) and one normal tissu...
EGAD00001000689 | EGA
UnknownKAT7 is a genetic vulnerability of acute myeloid leukemias driven by MLL rearrangements.
Not available
S-EPMC7610570 | biostudies-literature
GenomicsCRUK-ICGC Prostate Cancer Group Study
Prostate cancer somatic genomic sequencing data generated from 2011 onwards under auspices of the International Cancer Genome Consortium Prostate Cancer UK consortium (CRUK-ICGC Prostate Group), co-led by Colin Cooper and Ros Eeles, with other Principal Investigators (Brewer, Neal, Bova, McDermott, ...
EGAS00001000262 | EGA
UnknownOverexpression of Igf2-derived Mir483 inhibits Igf1 expression and leads to developmental growth restriction and metabolic dysfunction in mice.
Not available
S-EPMC7617298 | biostudies-literature
UnknownDexamethasone in Hospitalized Patients with Covid-19.
Not available
S-EPMC7383595 | biostudies-literature
UnknownAppraising the relevance of DNA copy number loss and gain in prostate cancer using whole genome DNA sequence data.
Not available
S-EPMC5628936 | biostudies-literature
GenomicsEGAS00001000262-sc-20170314 - samples
Whole Genome Sequencing Illumina HiSeq data from 111 men with prostate cancer. Samples were taken from primary tissue obtained at prostatectomy (target sequencing depth 50X) with matched blood control (target sequencing depth 30X). This data is from batches 4 to 6.
EGAD00001003225 | EGA
GenomicsThe Natural History of Human Prostate Cancer - samples
Affymetrix SNP6.0 genotype data for prostate cancer patients
EGAD00010000498 | EGA
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