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TranscriptomicsEctocarpus siliculosus response to copper stress
Transcriptomic study for the response of Ectocarpus siliculosus to mild copper stress (250 µg L-1 CuCl2) after 4h and 8h of exposure
ORGANISM(S): Ectocarpus siliculosus 
2014-03-10 | E-MTAB-1286 | biostudies-arrayexpress
TranscriptomicsThe Arabidopsis copper transport protein COPT2 and the responses under copper and iron deficiency.
Copper and iron are essential micronutrients for most living organisms because they participate as cofactors in biological processes including respiration, photosynthesis and oxidative stress protection. In many eukaryotic organisms, including yeast and mammals, copper and iron homeostases are highl...
ORGANISM(S): Arabidopsis thaliana 
2013-06-05 | E-GEOD-42642 | biostudies-arrayexpress
TranscriptomicsThe Two-component Signal Transduction System CopRS of Corynebacterium glutamicum is Required for Adaptation to Copper-excess Stress
Copper is an essential cofactor for many enzymes but at high concentrations it is toxic for the cell. Copper ion concentrations ≥50 µM inhibited growth of Corynebacterium glutamicum. The transcriptional response to 20 µM Cu2+ was studied using DNA microarrays and revealed 26 genes that showed a ≥3-f...
ORGANISM(S): Corynebacterium glutamicum ATCC 13032 
2011-09-04 | E-GEOD-27510 | biostudies-arrayexpress
no omics definedTranscription profiling of copper-stressed Pseudomonas aeruginosa
Anthropogenic pollution has increased the levels of heavy metals in the environment. Bacterial populations continue to thrive in highly polluted environments and bacteria must have mechanisms to counter heavy metal stress. We chose to examine the response of the environmentally-relevant organism P...
ORGANISM(S): Pseudomonas aeruginosa 
2007-10-24 | E-GEOD-4152 | biostudies-arrayexpress
TranscriptomicsGene expression response to copper toxicity between coastal and open ocean strains of marine Synechococcus
Marine cyanobacteria are thought to be the most sensitive of the phytoplankton groups to copper toxicity, yet little is known of the transcriptional response of marine Synechococcus to copper shock. Global transcriptional response to two levels of copper shock was assayed in both a coastal and an o...
ORGANISM(S): Synechococcus sp. CC9311 
2010-05-17 | E-GEOD-13910 | biostudies-arrayexpress
TranscriptomicsRNA-seq of Arabidopsis spl7 identifies two genes required for copper acquisition and a copper dependence of iron homeostasis
The transition metal copper (Cu) is an essential element for all living organisms. In plants, Cu plays key roles in electron transport chains of chloroplasts and mitochondria, as well as in cell wall metabolism, ethylene perception, molybdenum cofactor synthesis and oxidative stress protection. Beca...
ORGANISM(S): Arabidopsis thaliana 
2013-10-14 | E-GEOD-24696 | biostudies-arrayexpress
MetabolomicsMetabolomic analysis of alfalfa (Medicago sativa L.) root-symbiotic rhizobia responses under alkali stress
Alkaline salts (e.g., NaHCO3 and Na2CO3) causes more severe morphological and physiological damage to plants than neutral salts (e.g., NaCl and Na2SO4) due to differences in pH. The mechanism by which plants respond to alkali stress is not fully understood, especially in plants having symbotic relat...
2018-07-27 | MTBLS481 | MetaboLights
TranscriptomicsThe role of multi-copper oxidase CueO
The effect of a cueO mutation on global gene expression in E. coli has been analysed using whole genome oligonucleotide microarrays. A cueO mutant lacks a periplasmic multi-copper oxidase, an enzyme that is believed to be involved in the oxidation of cuprous and ferrous ions as well as phenolic comp...
ORGANISM(S): Escherichia coli 
2010-07-01 | E-GEOD-5177 | biostudies-arrayexpress
ProteomicsSynechocystis sp. PCC 6803(iron and/or copper starvation)-LC MS/MS
The protein abundance of Synechocystis in response to the given copper-iron combination was examined, then followed by comparative proteomic analyses to reveal the proteins associated with copper and iron stress. These data would provide a theoretical basis for understanding the relationship between...
ORGANISM(S): Synechocystis sp. PCC 6803 
2021-04-26 | PXD024873 | Pride
Starvation Iron Synechocystis sp. pcc 6803 Copper Proteome 
ProteomicsProteomics revealed the crosstalk between copper stress and cuproptosis
As an essential micronutrient element in organisms, copper controls a host of fundamental cellular functions. Recently, copper-dependent cell growth and proliferation have been defined as "cuproplasia". Conversely, “cuproptosis” represents copper-dependent cell death, a nonapoptotic manner. So far, ...
ORGANISM(S): Homo sapiens (Human) 
2022-11-17 | PXD037278 | Pride
Human Cuproptosis Copper stress Cancer 
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