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ModelsKervizic2008_Cholesterol_SREBP
Model of cholesterol regulation (with Boolean Formulae) (2008) This model is described in Dynamical modeling of the cholesterol regulatory pathway with Boolean networks ; Gwenael Kervizic and Laurent Corcos, BMC Systems Biology 2008, 2:99 doi: 10.1186/1752-0509-...
2005-01-01 | MODEL0568648427 | BioModels
TranscriptomicsEffect of SRSF2 over-expression in a human lung carcinoma cell line
We showed that the over-expression of the SR protein SRSF2 led to the regulation of transcript abundance of many genes. H358 cell line with 6 samples with SRSF2 over-expression and 6 samples as control.
ORGANISM(S): Homo sapiens 
2013-08-30 | E-GEOD-50467 | biostudies-arrayexpress
TranscriptomicsTaxanes
Gastric cancer has a dramatic prognosis, making it mandatory to analyze the possible benefit from novel drug associations. In this study, we looked at the combined effects of lovastatin, a cholesterol lowering drug, and docetaxel, a potent microtubule-stabilizing agent, in the HGT-1 human gastric ca...
ORGANISM(S): Homo sapiens 
2012-10-15 | E-MEXP-3391 | biostudies-arrayexpress
UnknownCELF proteins regulate CFTR pre-mRNA splicing: essential role of the divergent domain of ETR-3.
Not available
S-EPMC2978352 | biostudies-literature
TranscriptomicsCotranscriptional exon skipping in the genotoxic stress response
Pre-mRNA splicing is functionally coupled to transcription, and genotoxic stresses can enhance alternative exon inclusion by affecting elongating RNA polymerase II. We report here that various genotoxic stress inducers, including camptothecin, inhibit the interaction between EWS, an RNA polymerase I...
ORGANISM(S): Homo sapiens 
2010-06-09 | E-GEOD-21840 | biostudies-arrayexpress
ModelsCholesterol Regulatory Pathway
BACKGROUND: Qualitative dynamics of small gene regulatory networks have been studied in quite some details both with synchronous and asynchronous analysis. However, both methods have their drawbacks: synchronous analysis leads to spurious attractors and asynchronous analysis lacks computational effi...
2172 | Cell Collective
TranscriptomicsIdentification of a gene expression signature in colorectal adenoma in comparison with normal mucosa
We showed that a large number of genes were deregulated in colorectal adenomas in comparison with colorectal normal mucosae. 37 colorectal adenoma and 9 colorectal normal mucosa samples were analyzed. We generated a comparison between adenomas and normal mucosae.
ORGANISM(S): Homo sapiens 
2013-08-27 | E-GEOD-50114 | biostudies-arrayexpress
TranscriptomicsIdentification of a gene expression signature in colorectal adenocarcinoma in comparison with colorectal adenoma
We showed that a lot of genes were deregulated in colorectal adenocarcinomas in comparison with colorectal adenomas. 37 colorectal adenoma and 9 colorectal adenocarcinoma samples were analyzed. We generated a comparison between adenocarcinomas and adenomas.
ORGANISM(S): Homo sapiens 
2013-08-27 | E-GEOD-50115 | biostudies-arrayexpress
TranscriptomicsIdentification of a gene expression signature in colorectal adenocarcinoma in comparison with normal mucosa
We showed that a large number of genes were deregulated in colorectal adenocarcinomas in comparison with colorectal normal mucosae. 9 paired tumor-normal colorectal samples were analyzed. We generated a comparison between adenocarcinomas and normal mucosae.
ORGANISM(S): Homo sapiens 
2013-08-27 | E-GEOD-50117 | biostudies-arrayexpress
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