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MetabolomicsProtective Effects of Cordycepin against Oxaliplatin-Associated Drug-Induced Fatty Liver Disease and Preliminary Mechanistic Insights

Oxaliplatin (OXA) is a chemotherapeutic agent used to treat multiple malignancies. Although it predominantly causes hepatic sinusoidal obstruction syndrome, it also induces drug-induced fatty liver disease (DIFLD) via lipid metabolic dysregulation and oxidative stress, which persists post-cessati...

2025-09-04 | MTBLS12938 | MetaboLights
TranscriptomicsThe molecular effects of cordycepin on RNA synthesis in Saccharomyces cerevisiae
Cordycepin (3’ deoxyadenosine) is a biologically active compound that, when incorporated during RNA synthesis in vitro, provokes chain termination due to the absence of a 3’ hydroxyl moiety. We were interested in the effects mediated by this drug in vivo and analysed its impact on RNA metabolism...
ORGANISM(S): Saccharomyces cerevisiae 
2010-05-06 | E-GEOD-14619 | biostudies-arrayexpress
ProteomicsCordycepin Delays Postovulatory Aging of Mammalian Oocytes through Inhibition of Maternal mRNAs Degradation via DCP1A Polyadenylation Suppression
Postovulatory aging leads to the decline in oocyte quality and subsequent impairment of embryonic development, thereby reducing the success rates of assisted reproductive technology (ART). Nevertheless, potential preventative strategies to improve aging oocytes quality and the associated underlying ...
ORGANISM(S): Mus musculus (Mouse) 
2024-01-26 | PXD042600 | Pride
Aging oocytes Cordycepin 
GenomicsMCF-7 cordycepin polysome profiling
MCF-7 cordycepin polysome profiling
PRJNA1164713 | ENA
ProteomicsIntegration of genome, transcriptome and proteome of cordycepin high producing strains
Integration of genome, transcriptome and proteome of cordycepin high producing strains
ORGANISM(S): Cordyceps Militaris Cm01 
2026-03-28 | PXD076340 |
GenomicsMCF-7 cordycepin treatment (Agilent mouse 60K microarray)
MCF-7 cordycepin treatment (Agilent mouse 60K microarray)
PRJNA1162918 | ENA
GenomicsNIH3T3 serum stimulation and cordycepin treatment (Agilent mouse 60K microarray)
NIH3T3 serum stimulation and cordycepin treatment (Agilent mouse 60K microarray)
PRJNA1162803 | ENA
TranscriptomicsMCF-7 cordycepin polysome profiling
3’deoxyadenosine, also known as cordycepin, has been widely researched as a potential treatment for cancer, yielding promising results in tissue culture as well as in pre-clinical models. A wide variety of mechanisms of action have been proposed, with little agreement between different studies. Here...
ORGANISM(S): Homo sapiens 
2025-02-19 | GSE277765 | GEO
TranscriptomicsMCF-7 cordycepin treatment (Agilent mouse 60K microarray)
3’deoxyadenosine, also known as cordycepin, has been widely researched as a potential treatment for cancer, yielding promising results in tissue culture as well as in pre-clinical models. A wide variety of mechanisms of action have been proposed, with little agreement between different studies. Here...
ORGANISM(S): Homo sapiens 
2025-02-19 | GSE277620 | GEO
GenomicsThe anti-cancer effects of cordycepin in MA-10 mouse laydig tumor cells
The anti-cancer effects of cordycepin in MA-10 mouse laydig tumor cells
PRJNA448053 | ENA
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