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ProteomicsCryo-Electron Microscopy Shows Absence of Conventional Protein Corona on Lipid Nanoparticle Surfaces
Upon exposure to biological fluids, nanoparticles rapidly acquire a “protein corona”, a layer of adsorbed biomolecules, predominantly proteins. This layer significantly impacts nanoparticle pharmacokinetics and biodistribution, making detailed characterization vital for designing safe, and targeted ...
ORGANISM(S): Homo sapiens (Human) 
2026-09-14 | PXD070622 | Pride
Cryo-tem Lipid nanoparticles Protein corona Extracellular vesicles Corona shell Fusion 
ProteomicsPhotocatalytic proximity labeling technology for nanoparticle protein corona
We designed a photocatalytic proximity labeling technology for in situ labeling of corona proteins. When nanoparticles were exposed in plasma, they were immediately irradiated to induce the photocatalytic reaction, in which the inner Ce6 activated BP in the outer layer. BP was then released from nan...
ORGANISM(S): Mus Musculus 
2022-06-23 | PXD034930 |
ProteomicsNanoparticle Elasticity Affects Systemic Circulation lifetime by Modulating the Adsorption of Apolipoprotein A-I in Corona Formation
Nanoparticle elasticity plays crucial roles in determining nanoparticles’ physiological performances. However, the underlying mechanisms by which nanoparticle elasticity does so remain unknown.Using core-shell nanoparticles with a same PEGylated lipid bilayer shell yet cores differing in elasticity ...
ORGANISM(S): Mus Musculus 
2022-05-20 | PXD034004 |
TranscriptomicsHuman granulosa
We are human embryologists from center for reproductive medicinel of Anhui Provincial Hospital Affiliated to Anhui Medical University, and we have the expertise to do all that properly in humans. By deep sequencing, the current experiment determined the miRNA profile of two intrafollicular somatic c...
ORGANISM(S): Homo sapiens 
2014-07-14 | E-MTAB-2264 | biostudies-arrayexpress
UnknownMetal Coordination Induces Phase Segregation in Amphipolar Arborescent Copolymers with a Core-Shell-Corona Architecture.
Not available
S-EPMC9062874 | biostudies-literature
UnknownPolymer Topology Determines the Formation of Protein Corona on Core-Shell Nanoparticles.
Not available
S-EPMC7596783 | biostudies-literature
UnknownNanoparticle elasticity affects systemic circulation lifetime by modulating adsorption of apolipoprotein A-I in corona formation.
Not available
S-EPMC9288426 | biostudies-literature
UnknownAn ochered fossil marine shell from the mousterian of fumane cave, Italy.
Not available
S-EPMC3707824 | biostudies-literature
UnknownProtein-Sized Bright Fluorogenic Nanoparticles Based on Cross-Linked Calixarene Micelles with Cyanine Corona.
Not available
S-EPMC5756471 | biostudies-literature
UnknownTunable dual-emitting shell-crosslinked nano-objects as single-component ratiometric pH-sensing materials.
Not available
S-EPMC4262927 | biostudies-literature
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