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To investigate changes in cardiac transcription profiles caused by on-pump cardiac surgery, we collected myocardial samples, prior and after grafting, from patients undergoing on-pump coronary artery bypass grafting with cardiopulmonary bypass and cardiac arrest. The transcriptional profile of the m...
ORGANISM(S): Homo sapiens 
This SuperSeries is composed of the following subset Series: GSE12485: Changes in cardiac transcription profiles following off-pump coronary revascularization surgery GSE12486: Changes in cardiac transcription profiles following on-pump coronary artery bypass grafting Refer to individual Series
ORGANISM(S): Homo sapiens 
To investigate changes in cardiac transcription profiles caused by off-pump cardiac surgery, we collected myocardial samples, prior and after grafting, from patients undergoing off-pump coronary revascularization surgery. The transcriptional profile of the mRNA in these samples was measured with gen...
ORGANISM(S): Homo sapiens 
Anesthetic gases elicit organ protection in patients undergoing coronary artery bypass graft (CABG) surgery. This study aimed at identifying myocardial transcriptional phenotypes and anesthetic-induced changes in gene expression to predict cardiovascular biomarkers and cardiac function after off-pu...
ORGANISM(S): Homo sapiens 
In this placebo-controlled randomized controlled trial, we tested whether remote ischemic preconditioning (RIPC) elicited by four 5-minute cycles of 300 mmHg of cuff inflation/deflation of the lower limb would reduce myocardial necrosis in isoflurane-anesthetized patients undergoing on-pump coronary...
ORGANISM(S): Homo sapiens 
Atherosclerotic cardiovascular disease (CVD) is the major cause of death in patients with type 1 diabetes mellitus (T1DM). Alterations in the HDL proteome associate with prevalent CVD in T1DM. We therefore determined which proteins carried by HDL might predict incident CVD in T1DM patients. Using ta...
ORGANISM(S): Homo Sapiens 
2022-04-19 | PXD031854 | panorama
Detection of the altered expression of inflammation associated genes in patients’ blood can provide information regarding the stage of atherosclerotic plaque without undergoing invasive procedures. In the current study, the expression levels of miRNAs within the early stage and advanced stage athero...
ORGANISM(S): Homo sapiens 
Detection of the altered expression of inflammation associated genes in patients’ blood can provide information regarding the stage of atherosclerotic plaque without undergoing invasive procedures. In the current study, the expression levels of mRNAs within the early stage and advanced stage atheros...
ORGANISM(S): Homo sapiens 
The study aimed to uncover the biological significance of epicardial adipose tissue (EAT) in heart failure (HF) development by comparing its gene expression to that of subcutaneous adipose tissue (SAT). Tissue samples were collected from 21 patients undergoing coronary artery bypass graft surgery to...
ORGANISM(S): Homo sapiens 
New-onset postoperative atrial fibrillation (POAF) after coronary artery bypass grafting (CABG) is a major complication and the precise mechanism remains unclear. EVs have become a special intercellular information transmission system secreted from different cells. The present study aimed to identif...
ORGANISM(S): Homo Sapiens 
2025-12-11 | PXD071850 |
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