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ProteomicsDomain-selective folding of the tandem β-propeller protein Coronin 7 by the chaperonin CCT/TRiC
The Chaperonin containing tailless complex polypeptide 1 (CCT) or TCP-1 ring complex (TRiC) plays a central role in maintaining cellular homeostasis by supporting protein folding and damping protein aggregation. Besides the abundant cytoskeletal proteins, actin and tubulin, CCT/TRiC is emerging as a...
ORGANISM(S): Homo sapiens (Human) 
2026-02-20 | PXD073687 | Pride
Cct/tric Protein folding Chaperone-mediated folding Coronin 7 Bioid 
ProteomicsIdentification of novel Coronin 1A interacting proteins
Severe combined immunodeficiency 8 (IMD8) is caused by mutations in the human Coronin 1A (Coro1A). The clinical presentation of IMD8 patients is characterized by recurrent bacterial infections, suggesting an important role of Coro1A in innate immunity. To analyze the molecular mechanism of Coro1A du...
ORGANISM(S): Homo sapiens (Human) 
2017-06-29 | PXD004635 | Pride
Hl-60 cells Gfp nanotraps Maxquant Coronin 1a Co-immunoprecipitation Lc-ms/ms 
UnknownCoronin 1 Is Required for Integrin β2 Translocation in Platelets.
Not available
S-EPMC6982036 | biostudies-literature
UnknownActin-binding protein coronin 1A controls osteoclastic bone resorption by regulating lysosomal secretion of cathepsin K.
Not available
S-EPMC5353622 | biostudies-literature
TranscriptomicsIFN-γ and IL-17 synergistic anti-mycobacterial response via coronin-1A inhibition
This study investigates the molecular mechanism underlying the synergistic anti-mycobacterial effect of IFN-γ and IL-17. We performed microarray analysis on bone marrow-derived macrophages (BMDMs) from C57BL/6J mice infected with Mycobacterium tuberculosis H37Rv and treated with infection control, I...
ORGANISM(S): Mus musculus 
2025-11-11 | E-MTAB-16005 | biostudies-arrayexpress
UnknownT cell induced expression of Coronin-1A facilitates blood-brain barrier transmigration of breast cancer cells.
Not available
S-EPMC11682172 | biostudies-literature
UnknownTropomyosin Promotes Lamellipodial Persistence by Collaborating with Arp2/3 at the Leading Edge.
Not available
S-EPMC5644994 | biostudies-literature
UnknownCORO7 functions as a scaffold protein for the core kinase complex assembly of the Hippo pathway.
Not available
S-EPMC7949047 | biostudies-literature
ProteomicsCoro1a promotes the multivesicular body and plasma membrane fusion by facilitating PKM2-mediated SNAP-23 phosphorylation
During the formation of endosomal pathway-dependent extracellular vesicles (EVs), intraluminal vesicles in multivesicular bodies (MVBs) fuse with the plasma membrane (PM), releasing intraluminal vesicles to produce exosomes. Soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNAR...
ORGANISM(S): Homo Sapiens 
2025-12-07 | PXD071700 |
UnknownRaw data used to generate the structure of coronin-7 bound to the Arp2/3 complex
Not available
EMPIAR-12575 | biostudies-other
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