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ProteomicsProteomic profiling of PRLX-93936 and structurally similar compounds in pancreatic cancer cells. 
To determine the downstream molecular mechanism of PRLX-93936, we performed systematic proteomic profiling of cells treated with PRLX-93936, erastin, or JWZ-8-103. Results include global proteome profiling, ubiquitylation proteomics, and proximity labeling proteomics enabling comparison of drug-indu...
ORGANISM(S): Homo sapiens (Human) 
2025-08-15 | PXD059137 | Pride
Proximity labeling proteomics Pancreatic cancer Global proteome profiling Panc-1 cells Lfq Diapasef Ubiquitylation proteomics 
ProteomicsRNF43 G659fs is an oncogenic colorectal cancer mutation and sensitizes tumor cells to PI3K/mTOR inhibition
Fang L, Ford-Roshon D, Russo M, O'Brien C, Xiong X, Gurjao C, Grandclaudon M, Raghavan S, Corsello SM, Carr SA, Udeshi ND, Berstler J, Sicinska E, Ng K, Giannakis M. 2022. The RNF43_p.G659fs mutation occurs frequently in colorectal cancer, but its function remains poorly understood and there are no ...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2022-04-29 | MSV000089343 | MassIVE
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