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TranscriptomicsHigh-throughput sequencing of IgH gene in minor salivary glands from Sjögren’s syndrome patients reveals dynamic ectopic lymphoid structures with recirculating B cells
This study is the first of this kind performed on minor salivary glands (mSG) of patients with Sjögren’s Syndrome. It shows that B cells clones are able to circulate across different glands and once re-seeded in a different mSG to continue the process of somatic hypermutation and switching of the im...
ORGANISM(S): Homo sapiens 
2022-03-31 | E-MTAB-9065 | biostudies-arrayexpress
UnknownEfficient generation of a stable CHO-K1 cell line overexpressing the human water channel aquaporin-5 as tool to generate therapeutic antibodies.
Not available
S-EPMC11237030 | biostudies-literature
UnknownAccumulation of self-reactive naive and memory B cell reveals sequential defects in B cell tolerance checkpoints in Sjogren's syndrome.
Not available
S-EPMC4275206 | biostudies-literature
UnknownGeneration of restriction endonucleases barcode map to trace SARS-CoV-2 origin and evolution.
Not available
S-EPMC8175367 | biostudies-literature
UnknownH and L Chain Affinity Maturation and/or Fab N-Glycosylation Influence Immunoreactivity toward Neutrophil Extracellular Trap Antigens in Rheumatoid Arthritis Synovial B Cell Clones.
Not available
S-EPMC7167462 | biostudies-literature
UnknownCharacterization of a Synovial B Cell-Derived Recombinant Monoclonal Antibody Targeting Stromal Calreticulin in the Rheumatoid Joints.
Not available
S-EPMC6099528 | biostudies-literature
UnknownUnique expansion of IL-21+ Tfh and Tph cells under control of ICOS identifies Sjogren's syndrome with ectopic germinal centres and MALT lymphoma.
Not available
S-EPMC7677495 | biostudies-literature
UnknownNovel fully human IgG1 targeting folate receptor α demonstrates antitumor efficacy driven by avidity rather than monovalent binding affinity.
Not available
S-EPMC12827475 | biostudies-literature
UnknownAnti-β2glycoprotein I-induced neutrophil extracellular traps cause endothelial activation.
Not available
S-EPMC12316379 | biostudies-literature
ProteomicsCONNETTING ANTI-2GLYCOPROTEIN I ANTIBODIES, NETosis AND ENDOTHELIAL CELL ACTIVATION
This project aims to explore the intricate relationship between anti-β2glycoprotein I (aβ2GPI) antibodies, neutrophil extracellular traps (NETs), and endothelial cell activation in Antiphospholipid Syndrome (APS), an autoimmune disorder characterized by thrombotic events. This study tested the hypot...
ORGANISM(S): Homo sapiens (Human) 
2025-08-25 | PXD052010 | Pride
Netosis Autoimmune disorder Antiphospholipid syndrome Endothelial cell activation 
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