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TranscriptomicsRNA-seq analysis reveals significant effects of EGFR signaling on mesenchymal stem cells (MSC)
Purpose: Next-generation sequencing (NGS) has revolutionized systems-based analysis of cellular pathways. The goal of this study is to analyse the whole transcriptome of MSCs stimulated with TGFα in order to comprehensively assess the genes regulated by EGFR signalling Methods: Libraries of cDNA wer...
ORGANISM(S): Homo sapiens 
2015-06-26 | E-GEOD-60560 | biostudies-arrayexpress
UnknownVitamin C effect on mitoxantrone-induced cytotoxicity in human breast cancer cell lines.
Not available
S-EPMC4274052 | biostudies-literature
TranscriptomicsGene expression in epithelial and non-epithelial cells of renal origin
We aimed to define epithelial-specific genes in the kidney. In the developing mouse kidney at E12.5 epithelial cells are restricted to the ureteric bud, while mesenchymal cells surrounding the ureteric bud are non-epithelial. The mouse renal epithelial cell line mIMCD-3 was used to represent kidney ...
ORGANISM(S): Mus musculus 
2010-09-23 | E-GEOD-24295 | biostudies-arrayexpress
UnknownRole of the HGF/c-MET pathway in resistance to immune checkpoint inhibitors in advanced non-small cell lung cancer.
Not available
S-EPMC11698708 | biostudies-literature
TranscriptomicsHead and neck paragangliomas
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Homo sapiens 
2013-08-21 | E-GEOD-49615 | biostudies-arrayexpress
UnknownActivation of Fas/FasL pathway and the role of c-FLIP in primary culture of human cholangiocarcinoma cells.
Not available
S-EPMC5663931 | biostudies-literature
UnknownBactericidal antibodies against hypervirulent Neisseria meningitidis C field strains following MenC-CRM or MenACWY-CRM priming and MenACWY-CRM booster in children.
Not available
S-EPMC8078732 | biostudies-literature
TranscriptomicsGenome-wide analysis of the miR profile in human head and neck paraganglioma vs. Jacobson's (tympanic) nerve and SH-SY5Y neuroblastoma cells
The aim of the study was to assess whether changes in the expression of miRs could be implicated in the modulation of the NOTCH pathway in head and neck paragangliomas. Several miRs, notably including families (miR-34s, miR-200s) that target the NOTCH signaling pathway, resulted differentially expre...
ORGANISM(S): Homo sapiens 
2013-08-21 | E-GEOD-49190 | biostudies-arrayexpress
UnknownCytokinome profile of patients with type 2 diabetes and/or chronic hepatitis C infection.
Not available
S-EPMC3379982 | biostudies-literature
TranscriptomicsHigh-density genome-wide copy number variation (CNV) in human head and neck paragangliomas.
Gene-centric CNV analysis of 24 individual paraganglioma cases identified a list of 104 genes most significantly targeted by tumor-associated alterations. The NOTCH signaling pathway was the most significantly enriched term in the list. Overexpression of the relevant NOTCH pathway proteins in susten...
ORGANISM(S): Homo sapiens 
2013-08-21 | E-GEOD-49614 | biostudies-arrayexpress
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