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TranscriptomicsThe expanded regulatory T cell population in chronic filarial infection is highly heterogeneous, activated and suppresses dendritic cell function indirectly through effector T cells.
Natural regulatory T cells (nTregs) are known to increase during chronic infection or at the site tumor, though the exact mechanisms that contribute to their accumulation and mode of action remain unclear. We used flow cytometry and microarray analyses to delineate the phenotype of nTregs and their ...
ORGANISM(S): Homo sapiens 
2016-02-25 | E-GEOD-44767 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human filaria induced monocyte dysfunction and its reversal following treatment
To assess the function of peripheral blood derived monocytes in patently infected filaria patients (either Wuchereria bancrofti, Mansonella perstans, or both), we investigated the cytokine production and gene expression profile of these cells in filaria infected patients and compared them with those...
ORGANISM(S): Homo sapiens 
2008-06-12 | E-GEOD-2135 | biostudies-arrayexpress
ProteomicsSHMT2 controls Burkitt lymphoma cell survival by maintaining an oncogenic TCF3 transcriptional program
In this study, the human Burkitt’s Lymphoma cell line BL60 has been analysed via proteomic and phosphoproteomic analysis for effect of a knock down of the serine hydroxymethyltransferase 2 (shSHMT2) compared to a control construct (shGL2). Concerning the phosphoproteome, these results have been comp...
ORGANISM(S): Homo sapiens (Human) 
2023-03-10 | PXD018961 | Pride
B cell receptor One carbon metabolism Burkitt’s lymphoma 
UnknownSHMT2 inhibition disrupts the TCF3 transcriptional survival program in Burkitt lymphoma.
Not available
S-EPMC8938936 | biostudies-literature
UnknownService delivery challenges in HIV care during the first year of the COVID-19 pandemic: results from a site assessment survey across the global IeDEA consortium.
Not available
S-EPMC9742047 | biostudies-literature
UnknownChildren who acquire HIV infection perinatally are at higher risk of early death than those acquiring infection through breastmilk: a meta-analysis.
Not available
S-EPMC3285615 | biostudies-literature
UnknownIdentification of genetic risk loci and causal insights associated with Parkinson's disease in African and African admixed populations: a genome-wide association study.
Not available
S-EPMC10593199 | biostudies-literature
UnknownSocializing One Health: an innovative strategy to investigate social and behavioral risks of emerging viral threats.
Not available
S-EPMC8122533 | biostudies-literature
UnknownLow incidence of SARS-CoV-2, risk factors of mortality and the course of illness in the French national cohort of dialysis patients.
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S-EPMC7445552 | biostudies-literature
UnknownElective surgery cancellations due to the COVID-19 pandemic: global predictive modelling to inform surgical recovery plans.
Not available
S-EPMC7272903 | biostudies-literature
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