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TranscriptomicsEffect of AICAr and SAICAr accumulation on global transcription in the ade3 mutant
We investigated the effects of AICAr and SAICAr accumulation on the global transcriptome of yeast, comparing the ade3 mutant to the WT strain. The ade3 mutant strain (Y4143) was compared to the WT strain (Y2946). For each comparison, we made 2 technical replicates, swapping dyes.
ORGANISM(S): Saccharomyces cerevisiae 
2011-08-31 | E-GEOD-29021 | biostudies-arrayexpress
TranscriptomicsEffect of 5-amino-4-imidazolecarboxamide ribotide (AICAr) supplementation on global transcription
We investigated the effects of AICAr supplementation on the global transcriptome of Y2950. The Y2950 strain was grown with or without AICAr. For each comparison, we made 2 biological replicates, swapping dyes.
ORGANISM(S): Saccharomyces cerevisiae 
2011-08-31 | E-GEOD-29019 | biostudies-arrayexpress
TranscriptomicsRole of Ado1p in the transcriptional response associated with AICAr supplementation
We investigated the role of Ado1p associated with AICAr supplementation on the global transcriptome of Y3188. The Y3188 strain was grown with or without AICAr. For each comparison, we made 2 biological replicates, swapping dyes.
ORGANISM(S): Saccharomyces cerevisiae 
2011-08-31 | E-GEOD-29020 | biostudies-arrayexpress
TranscriptomicsEffect of adk1 knock-out mutation on global transcription
We investigated the effects of the variation in intracellular adenylic nucleotides pools due to the absence of the adenylate kinase Adk1p on the global yeast transcriptome. In this work, global transcription analyses were combined to measurements of intracellular nucleotides pools by HPLC. Keywords:...
ORGANISM(S): Saccharomyces cerevisiae 
2008-04-17 | E-GEOD-9553 | biostudies-arrayexpress
TranscriptomicsSingle cell RNA sequencing of subcutaneous nerves from 3-month-old control and mutant mice in the context of Neurofibromatosis type 1
Mutant mice (Nf1-KO) develop thicker subcutaneous nerves that progress for some of them in tumors. Analyzing and deciphering the cellular and molecular mechanisms of subcutaneous nerves from control and mutant mice of Neurofibromatosis type 1 at 3 months (before the development of the tumors) aims t...
ORGANISM(S): Mus musculus 
2025-08-30 | E-MTAB-13334 | biostudies-arrayexpress
TranscriptomicsRole of the AMP deaminase Amd1p in purines interconversion in Saccharomyces cerevisiae
In this work, we show that under specific conditions, defect in AMP deaminase activity strongly impairs yeast cell growth and we establish that AMP deaminase is required for correct balance between adenylic and guanylic nucleotides. Study of the Amd1p homologs, Yjl070p and Ybr284p, reveals that over...
ORGANISM(S): Saccharomyces cerevisiae 
2010-06-20 | E-GEOD-9557 | biostudies-arrayexpress
TranscriptomicsTrichoderma reesei transcript levels during mycoparasitism
To investigate the potential role in mycoparasitism, microarrays were used to examine T. reesei transcript levels when confronted with a potential prey (the plant pathogen Rhizoctonia solani) before contact, during first physical contact and during overgrowth of the host. Two biological pools by con...
ORGANISM(S): Hypocrea jecorina 
2011-07-01 | E-GEOD-23410 | biostudies-arrayexpress
TranscriptomicsTrichoderma virens transcript levels during mycoparasitism
Combating the action of plant pathogenic microorganisms by antagonistic or mycoparasitic fungi has been announced as an attractive biological alternative to the use of chemical fungicides since more than 20 years, and gains additional importance in current trends to environmentally friendly agricult...
ORGANISM(S): Hypocrea virens 
2011-07-01 | E-GEOD-19832 | biostudies-arrayexpress
TranscriptomicsTrichoderma atroviride transcript levels during mycoparasitism
To investigate the potential role in mycoparasitism, microarrays were used to examine T. atroviride transcript levels when confronted with a potential prey (the plant pathogen Rhizoctonia solani) before contact, during first physical contact and during overgrowth of the host. Two biological poolw by...
ORGANISM(S): Trichoderma atroviride 
2011-07-01 | E-GEOD-23382 | biostudies-arrayexpress
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