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UnknownEffects of alfacalcidol on cardiovascular outcomes according to alkaline phosphatase levels in the J-DAVID trial.
Not available
S-EPMC9475027 | biostudies-literature
TranscriptomicsEffect of ibuprofen on hippocampal gene expression in APP-PS1 mice
NSAIDs (non-steroidal anti-inflammatory drugs) inhibit cyclooxygenase (COX) enzymes and prevent Alzheimer'™s disease (AD) at preclinical stages in cognitively normal aging populations. We modeled NSAID prevention of memory impairment in AD model mice to identify novel targets of NSAID action. We fou...
ORGANISM(S): Mus musculus 
2016-06-14 | E-GEOD-67306 | biostudies-arrayexpress
UnknownDialysate calcium, alfacalcidol, and clinical outcomes: A post-hoc analysis of the J-DAVID trial.
Not available
S-EPMC9451061 | biostudies-literature
MetabolomicsPREDICT: untargeted metabolomic profiling in a Brassica napus (canola) breeding population by GC-MS

Genome-wide association studies (GWAS) identified thousands of genetic loci associated with complex plant traits, including many traits of agronomical importance. However, functional interpretation of GWAS results remains challenging because of large candidate regions due to linkage disequilibriu...

2023-11-20 | MTBLS8056 | MetaboLights
TranscriptomicsNext generation sequencing profiling identifies miR-574-3p and miR-660-5p as potential novel prognostic markers for breast cancer
Prognostication of Breast Cancer (BC) relies largely on traditional markers such as hormone or growth factors but due to their suboptimal specificities, it is challenging to identify the subset of patients who are likely to undergo recurrence and markers of higher specificity are sought to guide the...
ORGANISM(S): Homo sapiens 
2016-03-02 | E-GEOD-68085 | biostudies-arrayexpress
TranscriptomicsParallel Epigenomic and Transcriptomic Responses to Viral Infection in Honey Bees (Apis mellifera)
Here, we examined the transcriptional and epigenetic (DNA methylation) responses to viral infection in honey bee workers. One-day old worker honey bees were fed solutions containing Israeli Acute Paralysis Virus (IAPV), a virus which causes muscle paralysis and death and has previously been associa...
ORGANISM(S): Apis mellifera 
2015-02-06 | E-GEOD-65659 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of males from Drosophila simulans, Drosophila mauritiana, Drosophila melanogaster, Drosophila santomea, Drosophila sechellia, Drosophila teissieri, Drosophila yakuba
Co-expression of genes that physically cluster together is a common characteristic of eukaryotic transcriptomes. Identifying these groups of co-expressed genes is important to the functional annotation of genomes and understanding the evolutionary fates of the clustered genes. We used microarrays t...
ORGANISM(S): Drosophila melanogaster 
2008-06-16 | E-GEOD-7873 | biostudies-arrayexpress
UnknownD-2-Hydroxyglutarate Is Necessary and Sufficient for Isocitrate Dehydrogenase 1 Mutant-Induced MIR148A Promoter Methylation.
Not available
S-EPMC5984679 | biostudies-literature
TranscriptomicsTranscription profiling of mouse MyD88-deficient bone marrow-derived macrophages treated with Zymosan
Innate immune pattern recognition receptors play critical roles in pathogen detection and initiation of antimicrobial responses. We and others have previously demonstrated the importance of the beta-glucan receptor Dectin-1 in the recognition of pathogenic fungi by macrophages and dendritic cells, a...
ORGANISM(S): Mus musculus 
2008-06-14 | E-GEOD-6376 | biostudies-arrayexpress
ProteomicsDiscovery of biomarker candidates associated with the risk of short- and long-term relapse after infliximab withdrawal in Crohn’s patients: a proteomics-based study
Objective: A subset of Crohn’s disease (CD) patients experiences long-term remission after infliximab withdrawal. Biomarkers are needed to identify those patients. Design: New biomarkers of relapse were searched in the baseline serum of CD patients stopping infliximab when they were under combined t...
ORGANISM(S): Homo Sapiens 
2020-11-02 | PXD019434 | panorama
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