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ProteomicsTranslocase of the Outer Membrane (TOM complex) of hydrogenosomes in Trichomonas vaginalis
Mitochondria originated from α-proteobacterial endosymbionts, and the endosymbiont-to-organelle transition is tightly linked to the establishment of protein import pathways. The initial import of most proteins is mediated by the translocase of the outer membrane (TOM). Although TOM is common to all ...
ORGANISM(S): Trichomonas vaginalis G3 
2019-01-07 | PXD010850 | Pride
Mitochondria Tom complex Trichomonas vaginalis Protein import/translocation Hydrogenosomes 
ProteomicsTranslocase of the Outer Membrane (TOM complex) of hydrogenosomes in Trichomonas vaginalis
Mitochondria originated from α-proteobacterial endosymbionts, and the endosymbiont-to-organelle transition is tightly linked to the establishment of protein import pathways. The initial import of most proteins is mediated by the translocase of the outer membrane (TOM). Although TOM is common to all ...
ORGANISM(S): Trichomonas vaginalis 
2022-03-01 | PXD009474 | Pride
Mitochondria Tom complex Trichomonas vaginalis Protein import/translocation Hydrogenosomes 
ProteomicsReceptor-mediated recruitment of cytosolic J-proteins to the mitochondrial outer membrane promotes assembly of preprotein translocases
Mitochondria possess elaborate machineries for the import of preproteins from the cytosol. Cytosolic factors like Hsp70 chaperones and their co-chaperones, the J-proteins, guide preproteins to the mitochondrial surface. The translocase of the mitochondrial outer membrane (TOM) forms the entry gate f...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2018-11-26 | PXD008203 | Pride
Proteomics Cytosolic j-proteins Yeast Mitochondria Silac 
ProteomicsThe metabolite-controlled ubiquitin conjugase Ubc8 promotes mitochondrial protein import by enhancing assembly of the TOM complex - Data Set 2
Mitochondria are essential organelles that play a key role in energy metabolism. Transitions between glycolytic and respiring conditions induce considerable adaptations of the cellular proteome. These metabolism-dependent changes are particularly pronounced for the protein composition of mitochondri...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2022-10-15 | PXD033193 | Pride
Mitochondrial import Metabolic switch 
MetabolomicsIntegrated gut metabolome and microbiome fingerprinting reveals that dysbiosis precedes allergic inflammation in IgE‐mediated pediatric cow's milk allergy

BACKGROUND: IgE-mediated cow's milk allergy (IgE-CMA) is one of the first allergies to arise in early childhood and may result from exposure to various milk allergens, of which β-lactoglobulin (BLG) and casein are the most important. Understanding the underlying mechanisms behin...

2024-02-15 | MTBLS6768 | MetaboLights
UnknownFibroblastic reticular cells of the lymphoid tissues modulate T cell activation threshold during homeostasis via hyperactive cyclooxygenase-2/prostaglandin E2 axis.
Not available
S-EPMC5469856 | biostudies-literature
TranscriptomicsThe basal cm of leaf 4 of GA2OX::PLA1 (193-01) versus wild type in the growth chamber and the field (May-June 2015)
GA2OX::PLA1 transgenic plants and their none-transgenic siblings were grown in the field in Wetteren and in the growth chamber. In the field, we sampled three plants per plot (three plots were sown per genotype), resulting in three pools each consisting of three plants. Every pool represented a dif...
ORGANISM(S): Zea mays 
2019-10-16 | E-MTAB-8094 | biostudies-arrayexpress
TranscriptomicsThe basal cm of leaf 4 of GA2OX::PLA1 (193-01) versus wild type in the growth chamber and the field (May-June 2016)
GA2OX::PLA1 transgenic plants and their none-transgenic siblings were grown in the field in Wetteren and in the growth chamber. In the field, we sampled three plants per plot (three plots were sown per genotype), resulting in three pools each consisting of three plants. Every pool represented a dif...
ORGANISM(S): Zea mays 
2019-10-16 | E-MTAB-8095 | biostudies-arrayexpress
UnknownOutcomes of patients receiving urgent palliative radiotherapy for advanced lung cancer: an observational study.
Not available
S-EPMC11663318 | biostudies-literature
TranscriptomicsTranscription profiling of rat experimental model of knee osteoarthritis
OBJECTIVE: To analyze genome-wide changes in chondrocyte gene expression in a surgically induced model of early osteoarthritis (OA) in rats, to assess the similarity of this model to human OA, and to identify genes and mechanisms leading to OA pathogenesis. METHODS: OA was surgically induced in 5 ra...
ORGANISM(S): Rattus norvegicus 
2009-04-23 | E-GEOD-8077 | biostudies-arrayexpress
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