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ProteomicsA hybrid TIM complex mediates protein import into hydrogenosomes of Trichomonas vaginalis
Hydrogenosomes are a specific type of mitochondria that have adapted for life under anaerobiosis. Limited availability of oxygen has resulted in the loss of the membrane- associated respiratory chain, and consequently in the generation of minimal inner membrane potential (), and inefficient ATP synt...
ORGANISM(S): Trichomonas vaginalis 
2024-06-16 | PXD047649 | Pride
Presequence translocase-associated motor Parasite Protein import machinery Tim22 complex Mitochondria Tim23 complex Trichomonas vaginalis Hydrogenosomes 
ProteomicsThe divergent ER-mitochondria encounter structures (ERMES) are conserved in parabasalids but lost in several anaerobic lineages with hydrogenosomes.
The endoplasmic reticulum (ER)-mitochondria membrane contact sites (MCS) are extensively studied in aerobic eukaryotes, however, little is known about MCS in anaerobes with reduced forms of mitochondria named hydrogenosomes. In several eukaryotic lineages, the direct physical tether between ER and t...
ORGANISM(S): Trichomonas vaginalis 
2023-10-03 | PXD044071 | Pride
Hydrogenosomes Trichomonas vaginalis Anaerobiosis Endoplasmatic reticulum Ermes 
ProteomicsTranslocase of the Outer Membrane (TOM complex) of hydrogenosomes in Trichomonas vaginalis
Mitochondria originated from α-proteobacterial endosymbionts, and the endosymbiont-to-organelle transition is tightly linked to the establishment of protein import pathways. The initial import of most proteins is mediated by the translocase of the outer membrane (TOM). Although TOM is common to all ...
ORGANISM(S): Trichomonas vaginalis G3 
2019-01-07 | PXD010850 | Pride
Mitochondria Tom complex Trichomonas vaginalis Protein import/translocation Hydrogenosomes 
UnknownHydrogenosomes in the diplomonad Spironucleus salmonicida.
Not available
S-EPMC3778541 | biostudies-literature
UnknownConvergent Evolution of Hydrogenosomes from Mitochondria by Gene Transfer and Loss.
Not available
S-EPMC6993867 | biostudies-literature
UnknownPresence of a member of the mitochondrial carrier family in hydrogenosomes: conservation of membrane-targeting pathways between hydrogenosomes and mitochondria.
Not available
S-EPMC85448 | biostudies-literature
UnknownOrganelles in Blastocystis that blur the distinction between mitochondria and hydrogenosomes.
Not available
S-EPMC2428068 | biostudies-literature
UnknownN-Terminal Presequence-Independent Import of Phosphofructokinase into Hydrogenosomes of Trichomonas vaginalis.
Not available
S-EPMC4664869 | biostudies-literature
ProteomicsA mitochondrion-free eukaryote contains proteins preadapted for import into an exogenous mitochondrion-related organelle
The endobiotic flagellate Monocercomonoides exilis is the only eukaryote known to lose any form of mitochondria and all its associated proteins in its evolutionary past. This final stage of the mitochondrial evolutionary pathway may serve as a model to explain events at their very beginning such as ...
ORGANISM(S): Trichomonas vaginalis 
2023-03-11 | PXD035701 | Pride
Hydrogenosome Protein import Evolution of protein targeting : mitochondrion-free eukaryote 
UnknownFe-hydrogenase maturases in the hydrogenosomes of Trichomonas vaginalis.
Not available
S-EPMC1398061 | biostudies-literature
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