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MetabolomicsVeterinary trypanocidal benzoxaboroles are peptidase-activated prodrugs (T. congolense assay)

Livestock diseases caused by Trypanosoma congolense, T. vivax and T. brucei, collectively known as nagana, are responsible for billions of dollars in lost food production annually. There is an urgent need for novel therapeutics. Encouragingly, promising antitrypanosomal benzoxaboroles are under v...

2020-10-22 | MTBLS1309 | MetaboLights
ProteomicsAP-MS MudPIT run of Ino80 complex
File name explanation: Sc_Ino80_TAP_V2_P1_Ti_101: Sc = Saccharomyces cerevisiae (specie) Ino80 = bait protein TAP = tag V2 = lab instrument name(Velos_Elite2) P1 = biological replicate 1 Ti = LysC+Trypsin digestion 101 = MudPIT run 1 from 1st technical replicate
ORGANISM(S): Saccharomyces Cerevisiae (ncbitaxon:4932) 
2015-01-28 | MSV000079018 | MassIVE
ProteomicsAP-MS MudPIT run of Swr1 complex
File name explanation: Sc_Swr1_TAP_V2_P1_Ti_101: Sc = Saccharomyces cerevisiae (specie) Swr1 = bait protein TAP = tag V2 = lab instrument name(Velos_Elite2) P1 = biological replicate 1 Ti = LysC+Trypsin digestion 101 = MudPIT run 1 from 1st technical replicate
ORGANISM(S): Saccharomyces Cerevisiae (ncbitaxon:4932) 
2015-01-28 | MSV000079019 | MassIVE
TranscriptomicsMicroarray expression data from human renal mesangial cells (HMC) treated with a Cyclosporine A (CsA) time course.
HMCs were treated with CsA (4.2 M-BM-5M) for 0 12 and 48 hours. To exmaine global gene changes in the renal mesangium following CsA treatment in order to identify novel contributors to CsA-induced renal dysfunction Microarray analysis was used to identify novel mechanisms of CsA nephrotoxicity in th...
ORGANISM(S): Homo sapiens 
2012-04-03 | E-GEOD-30952 | biostudies-arrayexpress
ProteomicsMudPIT analyses of proteins associated with Piccolo and Bassoon in the presynaptic active zone
We used a 3-step protocol that separates lipid-associated proteins based on their buoyant density, size and charge. All steps were conducted either on ice or at 4C. Step 1 involved a sucrose density gradient centrifugation in which ca. 100 postnatal day 4 rat brains were homogenized in buffer A (5...
ORGANISM(S): Rattus Norvegicus (ncbitaxon:10116) 
2016-07-11 | MSV000079897 | MassIVE
TranscriptomicsIn vivo NCL-targeting affects breast cancer aggressiveness through miRNA regulation [NanoString]
Numerous studies have described the altered expression and the causal role of miRNAs in human cancer. However, to date efforts to modulate miRNA levels for therapeutic purposes have been challenging to implement. Here, we find that Nucleolin (NCL), a major nucleolar protein, post-transcriptionally r...
ORGANISM(S): Homo sapiens 
2012-11-02 | E-GEOD-41971 | biostudies-arrayexpress
TranscriptomicsArabidopsis Whole Genome 36-mer
Identification of novel transcribed sequences in Arabidopsis thaliana using high density genome tiling arrays.
ORGANISM(S): Arabidopsis thaliana 
2005-02-09 | E-GEOD-2247 | biostudies-arrayexpress
UnknownMultiorgan MRI findings after hospitalisation with COVID-19 in the UK (C-MORE): a prospective, multicentre, observational cohort study.
Not available
S-EPMC7615263 | biostudies-literature
UnknownStereoacuity in children with anisometropic amblyopia.
Not available
S-EPMC3223370 | biostudies-literature
UnknownStratified analyses refine association between TLR7 rare variants and severe COVID-19.
Not available
S-EPMC11320601 | biostudies-literature
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