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UnknownTelemedicine Use in Orthopaedic Surgery Varies by Race, Ethnicity, Primary Language, and Insurance Status.
Not available
S-EPMC8208394 | biostudies-literature
GenomicsOpen chromatin defined by DNaseI and FAIRE identifies regulatory elements that shape cell-type identity [DNase_seq].
The human body contains thousands of unique cell types, each with specialized functions. Cell identity is governed in large part by gene transcription programs, which are determined by regulatory elements encoded in DNA. To identify regulatory elements active in seven cell lines representative of di...
ORGANISM(S): Homo sapiens 
2011-06-29 | E-GEOD-30224 | biostudies-arrayexpress
GenomicsHigh-resolution genome-wide in vivo footprinting of diverse transcription factors in human cells (Dnase-seq)
Using DNaseI hypersensitivity (HS) assays (Dnase-seq), high resolution DNaseI digestion profiles were generated genome-wide in diverse human cell types. We showed that within general regions of DNaseI HS that are known to identify locations of gene regulatory elements, DNaseI digestion patterns all...
ORGANISM(S): Homo sapiens 
2010-11-18 | E-GEOD-25344 | biostudies-arrayexpress
GenomicsMicrobiota modulate transcription in the intestinal epithelium without remodeling the accessible chromatin landscape
We profiled transcriptome and accessible chromatin landscapes in intestinal epithelial cells (IECs) from mice reared in the presence or absence of microbiota. We show that regional differences in gene transcription along the intestinal tract were accompanied by major alterations in chromatin organiz...
ORGANISM(S): Mus musculus 
2014-06-07 | E-GEOD-57919 | biostudies-arrayexpress
TranscriptomicsTechnical Analysis of Fundulus heteroclitus cDNA Microarrays, experiment B
Analysis of the relationship between the amount of mRNA and the fluorescent signal from the microarray hybridizations. In addition, we measured expression for differences in RNA labeling and for the day on which RNA is prepared. Keywords: Gene expression Two-condition experiment, number of rounds o...
ORGANISM(S): Fundulus heteroclitus 
2010-05-15 | E-GEOD-12898 | biostudies-arrayexpress
GenomicsCell-type specific and combinatorial usage of diverse transcription factors revealed by genome-wide binding studies in multiple human cells [new ChIP-Seq samples]
Cellular diversity in a multicellular organism like the human is achieved in part by distinct programs of gene expression at the level of transcription, which in turn are mediated by transcription factors (TFs). However, there are few systematic studies of the genomic binding of different types of T...
ORGANISM(S): Homo sapiens 
2011-10-18 | E-GEOD-32692 | biostudies-arrayexpress
UnknownC-terminal modification of the insulin B:11-23 peptide creates superagonists in mouse and human type 1 diabetes.
Not available
S-EPMC5776820 | biostudies-literature
TranscriptomicsRetinoid X Receptor activation reverses the age-related deficiency in myelin debris phagocytosis and enhances remyelination
The efficiency of central nervous system (CNS) remyelination declines with age. This is in part due to an age-associated decline in the phagocytic removal of myelin debris, which contains inhibitors of oligodendrocyte progenitor cell differentiation. In this study we show that expression of genes i...
ORGANISM(S): Homo sapiens 
2015-11-04 | E-GEOD-66988 | biostudies-arrayexpress
GenomicsOpen Chromatin by DNaseI HS from ENCODE/OpenChrom(Duke University)
This data was generated by ENCODE. If you have questions about the data, contact the submitting laboratory directly (Terry Furey mailto:tsfurey@duke.edu). If you have questions about the Genome Browser track associated with this data, contact ENCODE (mailto:genome@soe.ucsc.edu). These tracks displa...
ORGANISM(S): Homo sapiens 
2011-10-14 | E-GEOD-32970 | biostudies-arrayexpress
GenomicsA Genome Wide Scan of Lung Cancer and Smoking

The majority of cases of lung cancer are the culmination of a dynamic process that begins with smoking initiation, proceeds through dependency and smoking persistence, continues with lung cancer development and ends with progression to disseminated disease or response to therapy and survival. We ...

phs000093.v2.p2 | EGA
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