Sort   by:  
 Page size 
ProteomicsNOD Mouse Islet Peptide Content Identification
Beta-cells produce hybrid insulin peptides (HIPs) by linking insulin fragments to other peptides through peptide bonds. HIPs have unique amino acid sequences and are targeted by autoreactive T cells in type 1 diabetes (T1D). Individuals with recent-onset T1D have significantly higher levels of HIP-r...
ORGANISM(S): Mus musculus (Mouse) 
2023-11-16 | PXD041616 | Pride
Hips Nod mouse Islet cells Peptides Lc-msms 
ProteomicsProteomics of Enriched Insulin Secretory Granules Fractionated by Size Exclusion Chromotography
Hybrid insulin peptides (HIPs) form in pancreatic beta-cells through the formation of peptide bonds between proinsulin fragments and other peptides. HIPs, which have been confidently identified in pancreatic islets by mass spectrometry, are targeted by CD4 T cells in subjects with Type 1 Diabetes (T...
ORGANISM(S): Mus musculus (Mouse) 
2023-11-16 | PXD032664 | Pride
Beta cell Proteins Insulin secretory granule Proteases 
Sort   by:  
 Page size