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UnknownDepletion of Abundant Sequences by Hybridization (DASH): using Cas9 to remove unwanted high-abundance species in sequencing libraries and molecular counting applications.
Not available
S-EPMC4778327 | biostudies-literature
ProteomicsHepatic Huwe1 loss protects mice from non-alcoholic fatty liver disease through lipid metabolic rewiring
Non-alcoholic fatty liver disease (NAFLD) is the most prevalent form of liver disease worldwide and is estimated to affect nearly a third of the population. Huwe1, also known as ARF-BP1, MULE, and HectH9, is a HECT (homology to E6-APC terminus)-domain E3 ubiquitin ligase originally identified as a b...
ORGANISM(S): Mus musculus (Mouse) 
2024-01-26 | PXD045279 | Pride
Nafld Rxr Ppar Steatosis 
TranscriptomicsPet-1 Switches Transcriptional Targets Postnatally to Regulate Maturation of Serotonin Neuron Excitability.
Newborn neurons enter an extended maturation stage, during which they acquire excitability characteristics crucial for development of presynaptic and postsynaptic connectivity. In contrast to earlier specification programs, little is known aboutthe regulatory mechanisms that control neuronal maturat...
ORGANISM(S): Mus musculus 
2016-01-08 | E-GEOD-74315 | biostudies-arrayexpress
UnknownSymptoms and quality of life in patients with suspected angina undergoing CT coronary angiography: a randomised controlled trial.
Not available
S-EPMC5529983 | biostudies-literature
UnknownThe mediational effects of FDG hypometabolism on the association between cerebrospinal fluid biomarkers and neurocognitive function.
Not available
S-EPMC4262609 | biostudies-literature
TranscriptomicsGenomic Analysis Reveals Distinct Mechanisms and Functional Classes of SOX10-Regulated Genes in Melanocytes [gene expression]
We performed ChIP-Seq analysis of SOX10, histone H3 lysine 27 acetylation (H3K27ac) and H3K27 trimethylation (H3K27me3) in melanocytes to profile the genomic binding sites of SOX10 and the chromatin landscape. In parallel, we generated Sox10 haploinsufficient cell lines using gene knockout approache...
ORGANISM(S): Mus musculus 
2015-07-03 | E-GEOD-69860 | biostudies-arrayexpress
Genomicsena-DATASET-UNIBE-07-04-2016-07:41:15:505-596 - samples
Mapped data (bam files) for high-throughput whole genome sequence data for 83 modern Aboriginal Australians
EGAD00001002001 | EGA
Genomics37a30206-29b3-47a0-90c4-eee326fe5b8b - samples
Genotype calls for 83 Aboriginal Australian genomes split by chromosomes. In short, genotypes were called individually with samtools. They were subsequently filtered with thresholds related to sequencing depth, location of variants, sequencing error, and strand bias. Once combined, the genotypes wer...
EGAD00001004155 | EGA
GenomicsRFMix
This dataset contains the per-chromosome RFMix input and output files for the local ancestry inference of 59 Aboriginal Australian genomes as reported in Malaspinas et al., 2016. Local ancestry was inferred assuming four mixing ancestral populations represented by: Europeans (27 individuals), Asians...
EGAD00010001575 | EGA
GenomicsMT alignment
Alignement including 83 MT AA sequences and 2 reference sequences, rCRS and RSRS
EGAD00010001574 | EGA
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