Crispr-cas systems

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Lab affiliation

Bioanalytical Mass Spectrometry Group, Max Planck Institute for Multidisciplinary Sciences, Germany (1)
Broad Institute (1)
Erasmus University Medical center (1)
Faculty of Biology, University of Freiburg, Freiburg, Germany (1)
LSC-EMBL Partnership Institute for Genome Editing Technologies, Life Sciences Center, Vilnius University, Saulėtekio al. 7, 10257 Vilnius, Lithuania (1)
Max-Planck Institute for Biophysical Chemistry (1)
Philipps University Marburg, Center for Synthetic Microbiology & Department of Chemistry, 35043 Marburg, Germany (1)
University of Oslo, Norway (1)
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Pyrococcus furiosus crRNAs associated with Cmr, Csa and Cst CRISPR-Cas systems

CRISPR-Cas immune systems function to defend prokaryotes against potentially harmful mobile genetic elements including viruses and plasmids. The multiple CRISPR-Cas systems (Types I, II, III) each recognize and target destruction of foreign invader nucleic acids via structurally and functionally div...

ORGANISM(S): Pyrococcus furiosus

2015-07-10 | E-GEOD-65781 | biostudies-arrayexpress

Deep sequencing data for PAM-SCANR tested CRISPR-Cas systems

In this work, we analyzed recognized PAM sequences from four CRISPR-Cas systems: E. coli I-E, B. halodurans I-C, S. thermophilus CR1 II-A, and F. novicida V. Cells containing functional PAMs were sorted using FACS and subsequently sequenced. Ranking of recognized PAMs from a positive screen

ORGANISM(S): Francisella tularensis subsp. novicida

2016-02-17 | E-GEOD-75718 | biostudies-arrayexpress

Deep sequencing data for PAM-SCANR tested CRISPR-Cas systems

PRJNA305147 | ENA

Type III-B CRISPR-Cas signaling-based cascade of proteolytic cleavages

Characteristic for type III CRISPR-Cas systems is the generation of cyclic oligoadenylate (cOA) molecules, which allosterically activate proteins carrying cognate sensory domains: CARF or SAVED. Here, we characterize a type III-B system associated set of genes from Haliangium ochraceum, containing t...

ORGANISM(S): Haliangium ochraceum DSM 14365

2025-05-06 | PXD046897 | Pride

Type iii crispr-cas